Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | ATM | Q13315 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10068936 | 0.89 | HSD17B10 (0.51) | HSD17B10ALDH1A1ATMSMN1; SMN2NPSR1 | |
| SCHEMBL8619431 | 0.87 | HSD17B10 (0.50) | HSD17B10ALDH1A1ATMSMN1; SMN2NPSR1 | |
| SCHEMBL4389273 | 0.83 | CA12 (0.52) | HSD17B10ALDH1A1ATMSMN1; SMN2NPSR1 | |
| SCHEMBL10068933 | 0.83 | KMO (0.51) | HSD17B10ALDH1A1ATMSMN1; SMN2NPSR1 | |
| SCHEMBL184149 | 0.81 | HSD17B10 (0.54) | HSD17B10ALDH1A1CA12CA1CA2 | |
| SCHEMBL10068703 | 0.81 | KMO (0.54) | HSD17B10ALDH1A1ATMSMN1; SMN2NPSR1 | |
| SCHEMBL2723391 | 0.80 | KMO (0.56) | ALDH1A1SMN1; SMN2KDM4EKMOLMNA | |
| SCHEMBL13406258 | 0.80 | ALDH1A1 (0.43) | HSD17B10ALDH1A1ATMSMN1; SMN2NPSR1 | |
| SCHEMBL10068935 | 0.79 | ALDH1A1 (0.46) | HSD17B10ALDH1A1ATMSMN1; SMN2NPSR1 | |
| SCHEMBL10068939 | 0.79 | CYP4F2 (0.40) | HSD17B10ALDH1A1ATMSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096153-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013096151-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2013-06-27 | — | — | WO | disclosed |