Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ALPL | P05186 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15054127 | 0.85 | PTGES (0.38) | ALPLSLC22A12PTGESFBP1PPARG | |
| SCHEMBL15054645 | 0.84 | CA1 (0.44) | SMN1; SMN2LMNAALDH1A1ALPLCA1 | |
| SCHEMBL15054144 | 0.83 | ALDH1A1 (0.43) | SMN1; SMN2LMNAALDH1A1ALPLKDM4E | |
| SCHEMBL15053855 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAALDH1A1ALPLKDM4E | |
| SCHEMBL15053983 | 0.80 | POLB (0.43) | SMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL15053744 | 0.79 | PTGES (0.39) | PTGES | |
| SCHEMBL25406823 | 0.79 | PPARG (0.32) | SMN1; SMN2GSTO1ALDH1A1ALPLKDM4E | |
| SCHEMBL15054633 | 0.79 | HTT (0.47) | SMN1; SMN2LMNAHTTALDH1A1KDM4E | |
| SCHEMBL15054709 | 0.79 | HTT (0.44) | SMN1; SMN2LMNAHTTALDH1A1KDM4E | |
| SCHEMBL30508423 | 0.79 | HTT (0.44) | SMN1; SMN2LMNAHTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096153-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2013-06-27 | — | — | WO | disclosed |