Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15054272 | 0.91 | MAPK1 (0.45) | MAPK1MAPTTP53GAANPSR1 | |
| SCHEMBL7573464 | 0.85 | MAPT (0.49) | MAPK1MAPTTP53GAANPSR1 | |
| SCHEMBL15054278 | 0.85 | GABRP (0.40) | — | |
| SCHEMBL21050728 | 0.83 | MAPT (0.46) | MAPK1MAPTTP53GAANPSR1 | |
| SCHEMBL10518080 | 0.83 | MEN1 (0.52) | MAPK1MAPTTP53GAANPSR1 | |
| SCHEMBL11438240 | 0.83 | MAPT (0.45) | HSP90AA1MAPK1MAPTTP53GAA | |
| SCHEMBL15055104 | 0.81 | GAA (0.46) | MAPK1MAPTTP53GAANPSR1 | |
| SCHEMBL11393991 | 0.81 | MAPT (0.48) | MAPK1MAPTTP53GAANPSR1 | |
| SCHEMBL2911498 | 0.81 | MEN1 (0.52) | MAPK1MAPTTP53GAANPSR1 | |
| SCHEMBL18530485 | 0.78 | KDM4E (0.44) | MAPK1MAPTTP53GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096151-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2013-06-27 | — | — | WO | disclosed |