Acrylamide

Acrylamide

SCHEMBL150558

C=CC(N)=O.CCC(O)(O)O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
TSHR P16473 3/20 0.58
FGFR4 P22455 1/20 0.58
THRB P10828 1/20 0.34
HPGD P15428 1/20 0.32
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.31
ZDHHC20 Q5W0Z9 1/20 0.30
ZDHHC2 Q9UIJ5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylamide SCHEMBL3731669 0.83
Acrylamide SCHEMBL28402180 0.83 ALDH1A1 (0.73) ALDH1A1TSHRFGFR4THRBHPGD
Acrylamide SCHEMBL6937505 0.82 ALDH1A1 (0.55) ALDH1A1TSHRFGFR4THRBHPGD
Acrylic Acid SCHEMBL30556472 0.81 LMNA (0.56) ALDH1A1TSHRFGFR4THRBHPGD
Acrylic Acid SCHEMBL29648053 0.81 LMNA (0.56) ALDH1A1TSHRFGFR4THRBHPGD
Acrylic Acid SCHEMBL29392442 0.81 LMNA (0.56) ALDH1A1TSHRFGFR4THRBHPGD
Acrylic Acid SCHEMBL29918659 0.81 LMNA (0.56) ALDH1A1TSHRFGFR4THRBHPGD
Acrylic Acid SCHEMBL27472496 0.81 LMNA (0.56) ALDH1A1TSHRFGFR4THRBHPGD
Acrylamide SCHEMBL8773893 0.80 TSHR (0.69) ALDH1A1TSHRFGFR4THRBHPGD
Acrylamide SCHEMBL39859 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012198-B2 Method for orthopoxvirus production and purification TRANSGENE S.A. (FR) 2015-04-21 US disclosed
US-20140073033-A1 METHOD FOR ORTHOPOXVIRUS PRODUCTION AND PURIFICATION TRANSGENE S.A. (FR) 2014-03-13 US disclosed
US-8609392-B2 Method for orthopoxvirus production and purification TRANSGENE S.A. (FR) 2013-12-17 US disclosed
US-20120190100-A1 ENZYMATIC COMPOSITION FOR THE DIGESTION OF CHICKEN EMBRYOS Transgene AS (FR) 2012-07-26 US disclosed
EP-2456461-A1 ENZYMATIC COMPOSITION FOR THE DIGESTION OF CHICKEN EMBRYOS Transgene SA (FR) 2012-05-30 EP disclosed
EP-2429580-A1 METHOD FOR ORTHOPOXVIRUS PRODUCTION AND PURIFICATION Transgene SA (FR) 2012-03-21 EP disclosed
US-20120058539-A1 METHOD FOR ORTHOPOXVIRUS PRODUCTION AND PURIFICATION TRANSGENE S.A. (FR) 2012-03-08 US disclosed
WO-2011009613-A1 ENZYMATIC COMPOSITION FOR THE DIGESTION OF CHICKEN EMBRYOS TRANSGENE SA (FR) 2011-01-27 WO disclosed
WO-2010130753-A1 METHOD FOR ORTHOPOXVIRUS PRODUCTION AND PURIFICATION TRANSGENE SA (FR) 2010-11-18 WO disclosed
US-7264958-B1 Method for obtaining a purified viral preparation TRANSGENE, S.A. (FR) 2007-09-04 US disclosed