SCHEMBL15056545

SCHEMBL15056545

CCN(CC)C(=O)C(F)(F)Oc1cc(F)c([N+](=O)[O-])cc1[N+](=O)[O-]

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.35
▸ MEN1 O00255 3/20 0.35
▸ KMT2A Q03164 3/20 0.35
▸ CYP2C9 P11712 2/20 0.35
▸ THRB P10828 1/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ ALDH1A1 P00352 4/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ COMT P21964 3/20 0.34
▸ LMNA P02545 3/20 0.34
▸ FTO Q9C0B1 2/20 0.34
▸ ABCC3 O15438 1/20 0.34
▸ ABCC4 O15439 1/20 0.34
▸ ABCB11 O95342 1/20 0.34
▸ GPR35 Q9HC97 1/20 0.34
▸ CYP3A4 P08684 2/20 0.33
▸ MAPK1 P28482 2/20 0.33
▸ RECQL P46063 1/20 0.33
▸ HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17875093 0.87 COMT (0.31) MAPTMEN1KMT2ACYP2C9THRB
SCHEMBL15056851 0.86 KMT2A (0.36) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL15057443 0.75 KDM4E (0.33) MAPTMEN1KMT2ATHRBCYP1A2
SCHEMBL17875092 0.73 KMT2A (0.33) MEN1KMT2AALDH1A1HTTTDP1
SCHEMBL15056865 0.72 GAA (0.48) MAPTMEN1KMT2ACYP2C9CYP1A2
SCHEMBL27989898 0.72 MEN1 (0.48) MAPTMEN1KMT2AALDH1A1RECQL
SCHEMBL27972345 0.72 RECQL (0.42) MAPTMEN1KMT2ACYP2C9CYP1A2
SCHEMBL8405075 0.70 MAPT (0.48) MAPTMEN1KMT2ACYP2C9CYP1A2
SCHEMBL15075566 0.70 SMN1; SMN2 (0.46) MAPTCYP2C9CYP1A2CYP2C19ALDH1A1
SCHEMBL27990087 0.69 RECQL (0.40) MAPTMEN1KMT2ACYP2C9CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9518045-B2 Process for manufacturing benzoxazinones BASF SE (DE) 2016-12-13 — — US disclosed
US-9518045-B2 Process for manufacturing benzoxazinones BASF SE (DE) 2016-12-13 — — US disclosed
US-9518045-B2 Process for manufacturing benzoxazinones BASF SE (DE) 2016-12-13 — — US disclosed
EP-2885281-B1 CARBAMAT-BENZOXAZINONES USEFUL FOR PREPARING TRIAZIN-BENZOXAZINONES BASF SE (DE) 2016-12-07 — — EP disclosed
EP-2885281-B1 CARBAMAT-BENZOXAZINONES USEFUL FOR PREPARING TRIAZIN-BENZOXAZINONES BASF SE (DE) 2016-12-07 — — EP disclosed
EP-2885296-B1 PROCESS FOR MANUFACTURING BENZOXAZINONES BASF SE (DE) 2016-06-29 — — EP disclosed
US-9359312-B2 Process for manufacturing benzoxazinones BASF SE (DE) 2016-06-07 — — US disclosed
US-9359312-B2 Process for manufacturing benzoxazinones BASF SE (DE) 2016-06-07 — — US disclosed
US-9359312-B2 Process for manufacturing benzoxazinones BASF SE (DE) 2016-06-07 — — US disclosed
US-9353070-B2 Carbamat-benzoxazinones BASF SE (DE) 2016-05-31 — — US disclosed
US-20140316131-A1 PROCESS FOR MANUFACTURING TRIAZINON-BENZOXAZINONES BASF SE (DE) 2014-10-23 — — US disclosed
US-20140316131-A1 PROCESS FOR MANUFACTURING TRIAZINON-BENZOXAZINONES BASF SE (DE) 2014-10-23 — — US disclosed
WO-2014026893-A1 CARBAMAT-BENZOXAZINONES BASF SE (DE) 2014-02-20 — — WO disclosed
WO-2014026928-A1 PROCESS FOR MANUFACTURING BENZOXAZINONES BASF SE (DE) 2014-02-20 — — WO disclosed
WO-2013092858-A1 PROCESS FOR MANUFACTURING TRIAZINON-BENZOXAZINONES BASF SE (DE) 2013-06-27 — — WO disclosed
WO-2013092859-A1 PROCESS FOR MANUFACTURING 4-SUBSTITUTED AMINO-BENZOXAZINONES BASF SE (DE) 2013-06-27 — — WO disclosed
WO-2013092856-A1 PROCESS FOR MANUFACTURING BENZOXAZINONES BASF SE (DE) 2013-06-27 — — WO disclosed
WO-2013092859-A1 PROCESS FOR MANUFACTURING 4-SUBSTITUTED AMINO-BENZOXAZINONES BASF SE (DE) 2013-06-27 — — WO disclosed
WO-2013092856-A1 PROCESS FOR MANUFACTURING BENZOXAZINONES BASF SE (DE) 2013-06-27 — — WO disclosed
WO-2013092858-A1 PROCESS FOR MANUFACTURING TRIAZINON-BENZOXAZINONES BASF SE (DE) 2013-06-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140316131-A1 PROCESS FOR MANUFACTURING TRIAZINON-BENZOXAZINONES CYP2B6, UGT1A6, UGT2B17 MAPT 2070/4885MEN1 4407/4885KMT2A 4000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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