Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17875093 | 0.87 | COMT (0.31) | KMT2AMEN1HCAR3TDP1 | |
| SCHEMBL15075518 | 0.87 | ESPL1 (0.31) | ESPL1ATMTDP1 | |
| SCHEMBL15056851 | 0.86 | KMT2A (0.36) | KMT2AHTTMEN1HPGDNPSR1 | |
| SCHEMBL17875097 | 0.78 | GAA (0.43) | KMT2AHTTMEN1NPSR1ALDH1A1 | |
| SCHEMBL17875095 | 0.76 | SMN1; SMN2 (0.41) | KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL15056985 | 0.75 | ALDH1A1 (0.47) | HTTATMTDP1ALDH1A1 | |
| SCHEMBL15056976 | 0.75 | TDP1 (0.43) | KMT2AHTTMEN1HPGDNPSR1 | |
| SCHEMBL17875094 | 0.75 | HTT (0.33) | KMT2AHTTMEN1HPGDATM | |
| SCHEMBL15056545 | 0.73 | MAPT (0.35) | KMT2AHTTMEN1HPGDTDP1 | |
| SCHEMBL15057255 | 0.68 | NOTUM (0.32) | KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3010895-B1 | PROCESS FOR MANUFACTURING 4-PROPARGYLATED AMINO-BENZOXAZINONES | BASF SE (DE) | 2017-08-09 | — | — | EP | disclosed |
| EP-2885296-B1 | PROCESS FOR MANUFACTURING BENZOXAZINONES | BASF SE (DE) | 2016-06-29 | — | — | EP | disclosed |