Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAC1 | P63000 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15056865 | 0.89 | GAA (0.48) | MAPTALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17875095 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAHPGDMAPTALDH1A1 | |
| SCHEMBL17875097 | 0.77 | GAA (0.43) | SMN1; SMN2LMNAMAPTALDH1A1CYP1A2 | |
| SCHEMBL15056851 | 0.73 | KMT2A (0.36) | SMN1; SMN2LMNAHPGDMAPTALDH1A1 | |
| SCHEMBL16406345 | 0.72 | SMN1; SMN2 (0.60) | SMN1; SMN2MAPTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL15056545 | 0.70 | MAPT (0.35) | SMN1; SMN2LMNAHPGDMAPTALDH1A1 | |
| SCHEMBL518729 | 0.69 | MAPT (0.76) | SMN1; SMN2LMNAMAPTALDH1A1CYP1A2 | |
| SCHEMBL20598781 | 0.68 | ALDH1A1 (0.49) | SMN1; SMN2LMNAMAPTALDH1A1CYP1A2 | |
| SCHEMBL30501358 | 0.68 | ALDH1A1 (0.49) | SMN1; SMN2LMNAMAPTALDH1A1CYP1A2 | |
| SCHEMBL16982491 | 0.68 | ALDH1A1 (0.72) | SMN1; SMN2LMNAHPGDMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9518045-B2 | Process for manufacturing benzoxazinones | BASF SE (DE) | 2016-12-13 | — | — | US | disclosed |
| US-9518045-B2 | Process for manufacturing benzoxazinones | BASF SE (DE) | 2016-12-13 | — | — | US | disclosed |
| EP-2885281-B1 | CARBAMAT-BENZOXAZINONES USEFUL FOR PREPARING TRIAZIN-BENZOXAZINONES | BASF SE (DE) | 2016-12-07 | — | — | EP | disclosed |
| US-9359312-B2 | Process for manufacturing benzoxazinones | BASF SE (DE) | 2016-06-07 | — | — | US | disclosed |
| US-9359312-B2 | Process for manufacturing benzoxazinones | BASF SE (DE) | 2016-06-07 | — | — | US | disclosed |
| US-9353070-B2 | Carbamat-benzoxazinones | BASF SE (DE) | 2016-05-31 | — | — | US | disclosed |
| US-9353070-B2 | Carbamat-benzoxazinones | BASF SE (DE) | 2016-05-31 | — | — | US | disclosed |
| US-20150299148-A1 | CARBAMAT-BENZOXAZINONES | BASF SE (DE) | 2015-10-22 | — | — | US | disclosed |
| US-20150299148-A1 | CARBAMAT-BENZOXAZINONES | BASF SE (DE) | 2015-10-22 | — | — | US | disclosed |
| US-20150218140-A1 | PROCESS FOR MANUFACTURING BENZOXAZINONES | BASF SE (DE) | 2015-08-06 | — | — | US | disclosed |
| US-9062012-B2 | Process for manufacturing 4-substituted amino-benzoxazinones | BASF SE (DE) | 2015-06-23 | — | — | US | disclosed |
| US-9000152-B2 | Process for manufacturing triazinon-benzoxazinones | BASF SE (DE) | 2015-04-07 | — | — | US | disclosed |
| US-9000152-B2 | Process for manufacturing triazinon-benzoxazinones | BASF SE (DE) | 2015-04-07 | — | — | US | disclosed |
| US-20140357861-A1 | PROCESS FOR MANUFACTURING BENZOXAZINONES | BASF SE (DE) | 2014-12-04 | — | — | US | disclosed |
| US-20140357861-A1 | PROCESS FOR MANUFACTURING BENZOXAZINONES | BASF SE (DE) | 2014-12-04 | — | — | US | disclosed |
| US-20140316131-A1 | PROCESS FOR MANUFACTURING TRIAZINON-BENZOXAZINONES | BASF SE (DE) | 2014-10-23 | — | — | US | disclosed |
| US-20140316131-A1 | PROCESS FOR MANUFACTURING TRIAZINON-BENZOXAZINONES | BASF SE (DE) | 2014-10-23 | — | — | US | disclosed |
| WO-2013092858-A1 | PROCESS FOR MANUFACTURING TRIAZINON-BENZOXAZINONES | BASF SE (DE) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013092859-A1 | PROCESS FOR MANUFACTURING 4-SUBSTITUTED AMINO-BENZOXAZINONES | BASF SE (DE) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013092856-A1 | PROCESS FOR MANUFACTURING BENZOXAZINONES | BASF SE (DE) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140357861-A1 | PROCESS FOR MANUFACTURING BENZOXAZINONES | XDH, CYP4X1, CYP3A5 | SMN1; SMN2 2784/4885LMNA 1232/4885HPGD 115/4885 |
| US-20140316131-A1 | PROCESS FOR MANUFACTURING TRIAZINON-BENZOXAZINONES | CYP2B6, UGT1A6, UGT2B17 | SMN1; SMN2 4603/4885LMNA 3362/4885HPGD 732/4885 |
| US-20150299148-A1 | CARBAMAT-BENZOXAZINONES | CYP4X1, XDH, CBX6 | SMN1; SMN2 3273/4885LMNA 1632/4885HPGD 434/4885 |
| US-20150218140-A1 | PROCESS FOR MANUFACTURING BENZOXAZINONES | CYP4X1, CYP3A5, CYP2B6 | SMN1; SMN2 3757/4885LMNA 1499/4885HPGD 300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.