SCHEMBL15057124

SCHEMBL15057124

CN(C)C(=O)C(F)(F)Oc1cccc(F)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 1/20 0.45
▸ MGLL Q99685 1/20 0.40
▸ RIPK1 Q13546 1/20 0.40
▸ NPC1 O15118 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ CETP P11597 2/20 0.39
▸ PPARG P37231 1/20 0.38
▸ PPARA Q07869 1/20 0.38
▸ MRGPRX4 Q96LA9 1/20 0.38
▸ USP2 O75604 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ PTGIR P43119 1/20 0.37
▸ ESR1 P03372 1/20 0.37
▸ ESR2 Q92731 1/20 0.37
▸ CES2 O00748 1/20 0.37
▸ CES1 P23141 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ MAOB P27338 1/20 0.37
▸ OPRM1 P35372 1/20 0.37
▸ LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15058493 0.85 HPGD (0.47) HPGDMGLLRIPK1NPC1RAB9A
SCHEMBL15059092 0.84 RIPK1 (0.40) HPGDRIPK1NPC1RAB9ACETP
SCHEMBL15076071 0.81 CETP (0.41) HPGDMGLLNPC1RAB9ACETP
SCHEMBL23519098 0.80 PPARG (0.45) HPGDNPC1RAB9APPARGPPARA
SCHEMBL15545838 0.79 KCNN4 (0.50) HPGDNPC1RAB9APPARGPPARA
SCHEMBL15058291 0.76 SLC6A4 (0.35) RIPK1RAB9AALDH1A1POLB
SCHEMBL17875096 0.76 HDAC1 (0.36) RAB9AALDH1A1
SCHEMBL15546762 0.76 POLB (0.49) PPARGPPARAMRGPRX4LMNAPOLB
SCHEMBL15059514 0.73 FFAR1 (0.39) HPGDRIPK1RAB9AKMT2A
SCHEMBL3373353 0.72 PPARA (0.54) PPARGPPARAKMT2AALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023247976-A1 DEUTERATED HERBICIDES BASED ON OXAZINONES AND 6-(TRIFLUOROMETHYL)PYRIMIDINE-2,4-DIONES REDAG CROP PROTECTION LTD (GB) 2023-12-28 — — WO disclosed
EP-3010895-B1 PROCESS FOR MANUFACTURING 4-PROPARGYLATED AMINO-BENZOXAZINONES BASF SE (DE) 2017-08-09 — — EP disclosed
EP-3184515-A1 PROCESS FOR MANUFACTURING 1,4-BENZOXAZINONES BASF SE (DE) 2017-06-28 — — EP disclosed
US-9518045-B2 Process for manufacturing benzoxazinones BASF SE (DE) 2016-12-13 — — US disclosed
US-9518045-B2 Process for manufacturing benzoxazinones BASF SE (DE) 2016-12-13 — — US disclosed
US-9518045-B2 Process for manufacturing benzoxazinones BASF SE (DE) 2016-12-13 — — US disclosed
EP-2885281-B1 CARBAMAT-BENZOXAZINONES USEFUL FOR PREPARING TRIAZIN-BENZOXAZINONES BASF SE (DE) 2016-12-07 — — EP disclosed
US-9512093-B2 Process for manufacturing 4-propargylated amino-benzoxazinones BASF SE (DE) 2016-12-06 — — US disclosed
EP-2794554-B1 PROCESS FOR MANUFACTURING ARYLOXYACETAMIDES BASF SE (DE) 2016-08-17 — — EP disclosed
EP-2794554-B1 PROCESS FOR MANUFACTURING ARYLOXYACETAMIDES BASF SE (DE) 2016-08-17 — — EP disclosed
EP-2794554-A1 PROCESS FOR MANUFACTURING ARYLOXYACETAMIDES BASF SE (DE) 2014-10-29 — — EP disclosed
EP-2794579-A1 PROCESS FOR MANUFACTURING 4-SUBSTITUTED AMINO-BENZOXAZINONES BASF SE (DE) 2014-10-29 — — EP disclosed
EP-2794599-A1 PROCESS FOR MANUFACTURING TRIAZINON-BENZOXAZINONES BASF SE (DE) 2014-10-29 — — EP disclosed
US-20140316131-A1 PROCESS FOR MANUFACTURING TRIAZINON-BENZOXAZINONES BASF SE (DE) 2014-10-23 — — US disclosed
WO-2014026928-A1 PROCESS FOR MANUFACTURING BENZOXAZINONES BASF SE (DE) 2014-02-20 — — WO disclosed
WO-2014026893-A1 CARBAMAT-BENZOXAZINONES BASF SE (DE) 2014-02-20 — — WO disclosed
WO-2013092850-A1 PROCESS FOR MANUFACTURING ARYLOXYACETAMIDES BASF SE (DE) 2013-06-27 — — WO disclosed
WO-2013092856-A1 PROCESS FOR MANUFACTURING BENZOXAZINONES BASF SE (DE) 2013-06-27 — — WO disclosed
WO-2013092858-A1 PROCESS FOR MANUFACTURING TRIAZINON-BENZOXAZINONES BASF SE (DE) 2013-06-27 — — WO disclosed
WO-2013092859-A1 PROCESS FOR MANUFACTURING 4-SUBSTITUTED AMINO-BENZOXAZINONES BASF SE (DE) 2013-06-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140316131-A1 PROCESS FOR MANUFACTURING TRIAZINON-BENZOXAZINONES CYP2B6, UGT1A6, UGT2B17 HPGD 732/4885MGLL 4641/4885RIPK1 3876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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