SCHEMBL1505841

SCHEMBL1505841

FC(F)(F)C(Cl)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
DPP4 P27487 2/20 0.38
F2 P00734 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HTR2A P28223 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
ACP3 P15309 1/20 0.34
CYP2D6 P10635 1/20 0.33
SRC P12931 1/20 0.33
IDO1 P14902 1/20 0.33
TDO2 P48775 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL28134621 0.87 SRC (0.42) TSHRALDH1A1ACP3CYP2D6SRC
SCHEMBL27486570 0.80 TSHR (0.46) TSHRDPP4F2ALDH1A1HTR2A
SCHEMBL8525796 0.78 TSHR (0.55) TSHRDPP4F2HTR2ATAAR1
SCHEMBL25703906 0.77 IDO1 (0.39) ALDH1A1IDO1TDO2
SCHEMBL27738562 0.76 TSHR (0.33) TSHRALDH1A1
SCHEMBL2176520 0.75 ESR1 (0.62) TSHRALDH1A1TAAR1CYP2D6
SCHEMBL48224 0.75 TSHR (0.41) TSHRDPP4F2ALDH1A1ACP3
SCHEMBL2789075 0.74 TSHR (0.50) TSHRDPP4F2HTR2ATAAR1
SCHEMBL29417551 0.73 CFTR (0.48) TSHRALDH1A1
SCHEMBL3111366 0.73 TSHR (0.48) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116661402-B Production control method and system for chemical materials 北京盛世利科技有限公司 2023-10-03 CN claimed
CN-116661402-A Production control method and system for chemical materials 北京盛世利科技有限公司 2023-08-29 CN claimed
CN-114988981-A Preparation method of alpha-trifluoromethyl arylpropyne compound 盐城工学院 2022-09-02 CN claimed
CN-112676307-A Method for reducing and recycling catalyst residues 江苏优普生物化学科技股份有限公司 2021-04-20 CN claimed
CN-107793292-A To the preparation method of trifluoromethyl benzyl chloride 江苏万隆科技有限公司 2018-03-13 CN claimed
CN-106117096-B A kind of synthetic method of asymmetric thioether 苏州大学 2018-01-19 CN claimed
CN-106349006-A Preparation method of 3-trifluoromethylphenylacetonitrile 大连奇凯医药科技有限公司 2017-01-25 CN claimed
CN-103897681-B A kind of oil gas field corrosion inhibiter and preparation method thereof 中国石油天然气集团公司 2016-06-08 CN claimed
CN-103898515-B A kind of oil-gas field inhibiter and preparation method thereof CHINA NATIONAL PETROLEUM CORPORATION (CN) 2016-03-09 CN claimed
CN-103897681-A Corrosion inhibitor for gas field and preparation method thereof CHINA NAT PETROLEUM CORP 2014-07-02 CN claimed
CN-103898515-A Corrosion inhibitor for gas field and preparation method thereof CHINA NAT PETROLEUM CORP 2014-07-02 CN claimed
CN-102260268-B Benzylthio acetamido acetylpyrazine triazole derivative as well as preparation thereof and application thereof QI YOUMAO 2013-04-03 CN claimed
CN-102260268-A Benzylthio acetamido acetylpyrazine triazole derivative as well as preparation thereof and application thereof 2011-11-30 CN claimed
CN-1142131-C Process for preparing meta-(trifluoromethyl)benzoic acid 上海试四赫维化工有限公司 2004-03-17 CN claimed
US-6201161-B1 Method of reducing benzaldehyde or benzotrihalide content in a mixture OCCIDENTAL CHEMICAL CORPORATION 2001-03-13 US claimed
CN-220370445-U Distillation condensing equipment 北京盛世利科技有限公司 2024-01-23 CN disclosed
CN-220370758-U Dampproof device 北京盛世利科技有限公司 2024-01-23 CN disclosed
US-4122256-A OPTICAL BRIGHTENERS HOECHST AKTIENGESELLSCHAFT (DE) 1978-10-24 US disclosed
US-4022897-A 4H-PYRIDO(1,2-A) PYRIMIDIN-4-ONE DERIVATIVES E. R. SQUIBB & SONS, INC. (US) 1977-05-10 US disclosed
US-3975448-A THERMAL STABILITY, CHEMICAL RESISTANCE TESSENDERLO CHEMIE S.A. (BE) 1976-08-17 US disclosed