SCHEMBL8525796

SCHEMBL8525796

ClC(c1ccccc1)C(Cl)(Cl)Cl

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.55
DPP4 P27487 2/20 0.41
F2 P00734 1/20 0.41
LMNA P02545 2/20 0.41
HTR2A P28223 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
HTT P42858 1/20 0.36
CYP2D6 P10635 1/20 0.36
SRC P12931 1/20 0.36
SLC6A4 P31645 1/20 0.35
TP53 P04637 1/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.35
HIF1A Q16665 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HRH1 P35367 1/20 0.35
MTOR P42345 1/20 0.35
RAB9A P51151 1/20 0.35
GRM7 Q14831 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5459793 0.79 TSHR (0.46) TSHRDPP4F2LMNAHTR2A
SCHEMBL2789075 0.78 TSHR (0.50) TSHRDPP4F2HTR2ATAAR1
SCHEMBL1505841 0.78 TSHR (0.50) TSHRDPP4F2HTR2ATAAR1
SCHEMBL4373477 0.77 TSHR (0.59) TSHRDPP4F2LMNAHTR2A
SCHEMBL28952946 0.76 TSHR (0.48) TSHRDPP4F2HTR2ATAAR1
SCHEMBL10947383 0.76 TSHR (0.42) TSHRDPP4F2LMNACYP2D6
SCHEMBL5152961 0.76 CYP1A2 (0.45) TSHRLMNAHTTCYP2D6SRC
SCHEMBL28443758 0.74 TSHR (0.46) TSHRDPP4F2LMNAHTR2A
SCHEMBL9250303 0.74 TSHR (0.64) TSHRLMNASLC6A4TP53HPGD
SCHEMBL1885792 0.74 TSHR (0.52) TSHRDPP4F2LMNAHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119019236-A Method for recycling halogenated organic pollutants by using transfer chlorination 中国科学院大连化学物理研究所 2024-11-26 CN claimed
CN-107924124-A Negative photoresist composition for I-line with excellent etching resistance 荣昌化学制品株式会社 2018-04-17 CN claimed
CN-106021887-A Health evaluation method for river mouth and bay ecological system 浙江省舟山海洋生态环境监测站 2016-10-12 CN claimed
CN-106010535-A Preparing method for Gd-Zn-Cu-In-S@ZnS core-shell quantum dot with adjustable emission wavelength 天津大学 2016-10-12 CN claimed
CN-105956406-A Evaluation method for ecosystem health of coastal waters 浙江省舟山海洋生态环境监测站 2016-09-21 CN claimed
CN-105265134-A Organic Chinese angelica production method and organic Chinese angelica product KUNMING JUNOUS AGROTECH CO LTD 2016-01-27 CN claimed
CN-102809554-B The nano sensitive material of biconjugate chlorphenyl trichloroethanes agricultural chemicals BIOCHEMICAL ENGINEERING COLLEGE OF BEIJING UNION UNIVERSITY (CN) 2015-08-12 CN claimed
CN-102998407-B Method for detecting pesticide residues in anti-inflammatory and analgesic bolus ZHANGZHOU PIEN TZE HUANG PHARM 2015-03-18 CN claimed
CN-102807263-B Method for degrading 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane pesticide in water by photocatalysis BIOCHEMICAL ENG COLLEGE BJ 2013-12-11 CN claimed
CN-102998407-A Method for detecting pesticide residues in anti-inflammatory and analgesic bolus ZHANGZHOU PIEN TZE HUANG PHARM 2013-03-27 CN claimed
CN-102809554-A Nano-sensitive material for dichlorodiphenyltrichloroethane pesticide BIOCHEMICAL ENG COLLEGE BJ 2012-12-05 CN claimed
CN-102807263-A Method for degrading 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane pesticide in water by photocatalysis BIOCHEMICAL ENG COLLEGE BJ 2012-12-05 CN claimed
EP-0121112-A1 2'-Deoxy-3-phosphonylmethyl nucleosides and method for their preparation Gesellschaft für Biotechnologische Forschung mbH (GBF) (DE) 1984-10-10 EP claimed
CN-117721634-A Amphiphilic functionalized graphene fiber and preparation method thereof 兰州东立龙信息技术有限公司 2024-03-19 CN disclosed
CN-114561210-B Zn-Cu-In-S quantum sheet, solar cell, and preparation method and application thereof 青岛大学 2023-10-13 CN disclosed
CN-116655868-A Solid phase microextraction adsorbent of bis-p-chlorophenyl trichloroethane 北京联合大学 2023-08-29 CN disclosed
US-5877924-A Thin film magnetic head including negative photoresist NEC CORPORATION (JP) 1999-03-02 US disclosed
US-4582925-A Tetramethylbiphenylcarboxylic acids and derivatives thereof STANDARD OIL COMPANY (INDIANA) (US) 1986-04-15 US disclosed
US-4127728-A FRIEDEL-CRAFTS CATALYST BAYER AKTIENGESELLSCHAFT (DE) 1978-11-28 US disclosed
US-3939084-A Functional fluid compositions containing substituted pyrimidines MONSANTO COMPANY (US) 1976-02-17 US disclosed