SCHEMBL48224

SCHEMBL48224

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(Cl)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
POLB P06746 1/20 0.32
DPP4 P27487 2/20 0.31
F2 P00734 1/20 0.31
ALDH1A1 P00352 1/20 0.31
ACP3 P15309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9224840 0.77 TSHR (0.35) TSHRALDH1A1
SCHEMBL7132919 0.77 AOC3 (0.41) TSHRPOLBALDH1A1
SCHEMBL9224273 0.76 TSHR (0.34) TSHRALDH1A1
SCHEMBL1505841 0.75 TSHR (0.50) TSHRDPP4F2ALDH1A1ACP3
SCHEMBL9297397 0.73 CES2 (0.38) TSHRPOLBDPP4F2ALDH1A1
SCHEMBL9225482 0.71 TSHR (0.37) TSHR
SCHEMBL10040021 0.70 LMNA (0.43) TSHRALDH1A1
SCHEMBL9220176 0.69 TSHR (0.35) TSHR
SCHEMBL8525796 0.69 TSHR (0.55) TSHRDPP4F2
SCHEMBL28832809 0.68 POLB (0.33) TSHRPOLBDPP4F2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129025-B2 Fluorotelomer grafted polyaniline containing intermediate transfer members XEROX CORPORATION (US) 2012-03-06 US claimed
US-20100247919-A1 FLUOROTELOMER GRAFTED POLYANILINE CONTAINING INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2010-09-30 US claimed