SCHEMBL15058855

SCHEMBL15058855

COC(=O)CCCCCCCC1OC1CCCCCCCC(=O)OC

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.54
LMNA P02545 2/20 0.48
ALDH1A1 P00352 1/20 0.48
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.42
KMT2A Q03164 1/20 0.41
EPHX2 P34913 3/20 0.41
HPGD P15428 1/20 0.41
PABPC1 P11940 1/20 0.40
APOBEC3A P31941 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40
RECQL P46063 1/20 0.39
CTSK P43235 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8434072 0.98 TSHR (0.52) TSHRLMNAALDH1A1TDP1L3MBTL1
SCHEMBL15167015 0.93 POLB (0.47) TSHRLMNAALDH1A1EPHX2CTSK
SCHEMBL13450360 0.93 POLB (0.47) TSHRLMNAALDH1A1EPHX2CTSK
SCHEMBL17678892 0.93 POLB (0.47) TSHRLMNAALDH1A1EPHX2CTSK
SCHEMBL20577392 0.93 TSHR (0.47) TSHRLMNAALDH1A1TDP1L3MBTL1
SCHEMBL2481579 0.93 TSHR (0.47) TSHRLMNAALDH1A1TDP1L3MBTL1
SCHEMBL11089141 0.93 POLB (0.47) TSHRLMNAALDH1A1EPHX2CTSK
SCHEMBL15167195 0.93 POLB (0.47) TSHRLMNAALDH1A1EPHX2CTSK
SCHEMBL403548 0.93 POLB (0.47) TSHRLMNAALDH1A1EPHX2CTSK
SCHEMBL15167017 0.93 POLB (0.47) TSHRLMNAALDH1A1EPHX2CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220396545-A1 METHODS OF MAKING OLEFINIC E- AND Z-ISOMERS VERBIO SE (DE) 2022-12-15 US disclosed
US-11420926-B2 Methods of making olefinic E- and Z-isomers VERBIO VEREINIGTE BIOENERGIE AG (DE) 2022-08-23 US disclosed
US-20210122697-A1 METHODS OF MAKING OLEFINIC E- AND Z-ISOMERS VERBIO SE (DE) 2021-04-29 US disclosed
EP-3630741-A1 METHODS OF MAKING OLEFINIC E- AND Z-ISOMERS Verbio Vereinigte Bioenergie AG (DE) 2020-04-08 EP disclosed
WO-2018220088-A1 METHODS OF MAKING OLEFINIC E- AND Z-ISOMERS XIMO AG (CH) 2018-12-06 WO disclosed
US-9302972-B2 Process for the preparation of azeleic acid from 9-octadecenedioic acid DSM IP ASSETS B.V. (NL) 2016-04-05 US disclosed
US-20150183704-A1 PROCESS FOR THE PREPARATION OF AZELEIC ACID FROM 9-OCTADECENEDIOIC ACID DSM IP ASSETS B.V. (NL) 2015-07-02 US disclosed
EP-2776385-A1 PROCESS FOR THE PREPARATION OF AZELEIC ACID FROM 9-OCTADECENEDIOIC ACID DSM IP Assets B.V. (NL) 2014-09-17 EP disclosed
WO-2013092353-A1 PROCESS FOR THE PREPARATION OF AZELEIC ACID FROM 9-OCTADECENEDIOIC ACID DSM IP ASSETS B.V. (NL) 2013-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11420926-B2 Methods of making olefinic E- and Z-isomers SQLE, OXER1, POR TSHR 4056/4885LMNA 2664/4885ALDH1A1 325/4885
US-20210122697-A1 METHODS OF MAKING OLEFINIC E- AND Z-ISOMERS SQLE, OXER1, POR TSHR 4056/4885LMNA 2664/4885ALDH1A1 325/4885
US-20150183704-A1 PROCESS FOR THE PREPARATION OF AZELEIC ACID FROM 9-OCTADECENEDIOIC ACID APEH, ALOX5, HAAO TSHR 2183/4885LMNA 1810/4885ALDH1A1 500/4885
US-20220396545-A1 METHODS OF MAKING OLEFINIC E- AND Z-ISOMERS CYP2F1, OXER1, SQLE TSHR 4229/4885LMNA 2739/4885ALDH1A1 381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.