Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.62 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.62 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 4/20 | 0.42 |
| ▸ | CES1 | P23141 | 4/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16295160 | 1.00 | GPR84 (0.62) | GPR84FFAR1FFAR4FNTAFNTB | |
| SCHEMBL8674293 | 1.00 | GPR84 (0.62) | GPR84FFAR1FFAR4FNTAFNTB | |
| SCHEMBL9285313 | 1.00 | GPR84 (0.62) | GPR84FFAR1FFAR4FNTAFNTB | |
| SCHEMBL801323 | 0.97 | GPR84 (0.57) | GPR84FFAR1FFAR4FNTAFNTB | |
| SCHEMBL59985 | 0.88 | — | — | |
| SCHEMBL10958653 | 0.88 | OR51E2 (0.56) | GPR84FFAR1FFAR4OR51E2MAPK1 | |
| SCHEMBL10957816 | 0.88 | OR51E2 (0.56) | GPR84FFAR1FFAR4OR51E2MAPK1 | |
| SCHEMBL10961559 | 0.88 | OR51E2 (0.56) | GPR84FFAR1FFAR4OR51E2MAPK1 | |
| SCHEMBL10959418 | 0.88 | OR51E2 (0.56) | GPR84FFAR1FFAR4OR51E2MAPK1 | |
| SCHEMBL10961683 | 0.88 | OR51E2 (0.56) | GPR84FFAR1FFAR4OR51E2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210403410-A1 | OPHTHALMIC FORMULATION | WESTERN SYDNEY UNIV (AU) | 2021-12-30 | — | — | US | disclosed |
| US-20200190015-A1 | OPHTHALMIC FORMULATION | WESTERN SYDNEY UNIV (AU) | 2020-06-18 | — | — | US | disclosed |
| US-10385003-B2 | Ophthalmic formulation | MILLAR THOMAS (AU) | 2019-08-20 | — | — | US | disclosed |
| EP-3459929-A1 | OPHTHALMIC FORMULATION | University of Western Sydney (AU) | 2019-03-27 | — | — | EP | disclosed |
| EP-2794550-B1 | OPHTHALMIC FORMULATION | UNIV OF WESTERN SYDNEY (AU) | 2019-02-20 | — | — | EP | disclosed |
| US-20140377335-A1 | OPHTHALMIC FORMULATION | UNIV WESTERN SYDNEY (AU) | 2014-12-25 | — | — | US | disclosed |
| EP-2794550-A2 | OPHTHALMIC FORMULATION | University of Western Sydney (AU) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013091020-A2 | OPHTHALMIC FORMULATION | UNIVERSITY OF WESTERN SYDNEY (AU) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200190015-A1 | OPHTHALMIC FORMULATION | C9, C1R, F12 | GPR84 1353/4885FFAR1 290/4885FFAR4 787/4885 |
| US-10385003-B2 | Ophthalmic formulation | C9, C1R, C1S | GPR84 1353/4885FFAR1 302/4885FFAR4 734/4885 |
| US-20140377335-A1 | OPHTHALMIC FORMULATION | C9, C1R, C1S | GPR84 1353/4885FFAR1 302/4885FFAR4 734/4885 |
| US-20210403410-A1 | OPHTHALMIC FORMULATION | C9, C1R, C5 | GPR84 2196/4885FFAR1 470/4885FFAR4 753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.