⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL801323 | 0.91 | GPR84 (0.57) | — | |
| SCHEMBL9285313 | 0.88 | GPR84 (0.62) | — | |
| SCHEMBL16295160 | 0.88 | GPR84 (0.62) | — | |
| SCHEMBL15059014 | 0.88 | GPR84 (0.62) | — | |
| SCHEMBL8674293 | 0.88 | GPR84 (0.62) | — | |
| SCHEMBL16554876 | 0.83 | OR51E2 (0.59) | — | |
| SCHEMBL20163309 | 0.83 | CAMK2A (0.59) | — | |
| Butyl Alcohol SCHEMBL910008 | 0.82 | CES1 (0.59) | — | |
| SCHEMBL10959418 | 0.80 | OR51E2 (0.56) | — | |
| SCHEMBL10958653 | 0.80 | OR51E2 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4056706-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL AND RELATED METHODS | Genomatica, Inc. (US) | 2022-09-14 | — | — | EP | claimed |
| US-11401534-B2 | Microorganisms for the production of 1,4- butanediol and related methods | GENOMATICA, INC. (US) | 2022-08-02 | — | — | US | claimed |
| CN-107384846-A | Produce microorganism and the correlation technique of 1,4 butanediols | 基因组股份公司 | 2017-11-24 | — | — | CN | claimed |
| US-9523105-B2 | Fermentation route for the production of levulinic acid, levulinate esters and valerolactone and derivatives thereof | ARZEDA CORPORATION (US) | 2016-12-20 | — | — | US | claimed |
| EP-2588598-B1 | METHOD FOR THE PREPARATION OF HYDROXY ACIDS | METABOLIC EXPLORER SA (FR) | 2016-03-09 | — | — | EP | claimed |
| US-20150337342-A1 | BIOSYNTHETIC PATHWAYS AND METHODS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2015-11-26 | — | — | US | claimed |
| US-9121041-B2 | Method for the preparation of diols | METABOLIC EXPLORER (FR) | 2015-09-01 | — | — | US | claimed |
| EP-2379730-B1 | METHOD FOR THE PREPARATION OF DIOLS | METABOLIC EXPLORER SA (FR) | 2015-07-22 | — | — | EP | claimed |
| CN-102341502-B | Process for the preparation of diols | METABOLIC EXPLORER SA | 2015-07-01 | — | — | CN | claimed |
| US-8911978-B2 | Method for the preparation of hydroxy acids | METABOLIC EXPLORER (FR) | 2014-12-16 | — | — | US | claimed |
| WO-2012127057-A1 | PROCESS FOR THE ENZYMATIC PRODUCTION OF C4 COMPOUNDS FROM C6 SUBSTRATES | SIEBER VOLKER (DE) | 2012-09-27 | — | — | WO | claimed |
| EP-2503003-A1 | Synthetic pathway for the production of alcohols or amines | Sieber, Volker (DE) | 2012-09-26 | — | — | EP | claimed |
| US-8129156-B2 | Microorganisms for the production of 1,4-butanediol | GENOMATICA, INC. (US) | 2012-03-06 | — | — | US | claimed |
| CN-102341502-A | Process for the preparation of diols | METABOLIC EXPLORER SA | 2012-02-01 | — | — | CN | claimed |
| WO-2012001003-A1 | METHOD FOR THE PREPARATION OF HYDROXY ACIDS | METABOLIC EXPLORER (FR) | 2012-01-05 | — | — | WO | claimed |
| EP-2379730-A1 | METHOD FOR THE PREPARATION OF DIOLS | Metabolic Explorer (FR) | 2011-10-26 | — | — | EP | claimed |
| WO-2011066076-A1 | MICROORGANISMS AND METHODS FOR THE COPRODUCTION OF 1,4-BUTANEDIOL AND GAMMA-BUTYROLACTONE | GENOMATICA, INC. (US) | 2011-06-03 | — | — | WO | claimed |
| US-20110014669-A1 | Production of 1,4 Butanediol in a Microorganism | MICROBIA, INC. | 2011-01-20 | — | — | US | claimed |
| WO-2010085731-A2 | PRODUCTION OF 1,4 BUTANEDIOL IN A MICROORGANISM | MICROBIA, INC. (US) | 2010-07-29 | — | — | WO | claimed |
| WO-2010076324-A1 | METHOD FOR THE PREPARATION OF DIOLS | METABOLIC EXPLORER (FR) | 2010-07-08 | — | — | WO | claimed |