Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | CASP7 | P55210 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15057097 | 0.84 | GAA (0.43) | KDM4EALOX15CASP1CASP7HSD17B10 | |
| SCHEMBL15057669 | 0.78 | ATM (0.63) | KDM4EALOX15CASP1CASP7HSD17B10 | |
| SCHEMBL15057514 | 0.73 | ATM (0.48) | KDM4EALOX15CASP1CASP7HSD17B10 | |
| SCHEMBL10046477 | 0.72 | ALDH1A1 (0.46) | KDM4EALOX15HSD17B10NPSR1MAPT | |
| SCHEMBL17970059 | 0.71 | ATM (0.58) | KDM4EALOX15CASP1CASP7HSD17B10 | |
| SCHEMBL15057002 | 0.69 | ATM (0.71) | KDM4ECASP1CASP7HSD17B10TSHR | |
| SCHEMBL15057078 | 0.69 | ATM (0.71) | KDM4ECASP1CASP7HSD17B10TSHR | |
| SCHEMBL15056476 | 0.69 | ATM (0.71) | KDM4ECASP1CASP7HSD17B10TSHR | |
| SCHEMBL15057200 | 0.69 | ATM (0.71) | KDM4ECASP1CASP7HSD17B10TSHR | |
| SCHEMBL15057376 | 0.69 | ATM (0.71) | KDM4ECASP1CASP7HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794572-B1 | ACRIDINEDIONE DERIVATIVES FOR TREATING PIGMENTATION DISORDERS AND AGEING OF THE SKIN | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2016-08-03 | — | — | EP | claimed |
| US-20140348768-A1 | ACRIDINEDIONE DERIVATIVES FOR TREATING PIGMENTATION DISORDERS AND AGEING OF THE SKIN | PIERRE FABRE DERMO COSMETIQUE (FR) | 2014-11-27 | — | — | US | claimed |
| EP-2794572-A1 | ACRIDINEDIONE DERIVATIVES FOR TREATING PIGMENTATION DISORDERS AND AGEING OF THE SKIN | Pierre Fabre Dermo-Cosmétique (FR) | 2014-10-29 | — | — | EP | claimed |
| WO-2013093019-A1 | ACRIDINEDIONE DERIVATIVES FOR TREATING PIGMENTATION DISORDERS AND AGEING OF THE SKIN | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-06-27 | — | — | WO | claimed |
| US-9493421-B2 | Acridinedione derivatives for treating pigmentation disorders and ageing of the skin | PIERRE FABRE DERMO COSMETIQUE (FR) | 2016-11-15 | — | — | US | disclosed |
| US-9493421-B2 | Acridinedione derivatives for treating pigmentation disorders and ageing of the skin | PIERRE FABRE DERMO COSMETIQUE (FR) | 2016-11-15 | — | — | US | disclosed |
| US-9493421-B2 | Acridinedione derivatives for treating pigmentation disorders and ageing of the skin | PIERRE FABRE DERMO COSMETIQUE (FR) | 2016-11-15 | — | — | US | disclosed |
| EP-2794572-B1 | ACRIDINEDIONE DERIVATIVES FOR TREATING PIGMENTATION DISORDERS AND AGEING OF THE SKIN | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2016-08-03 | — | — | EP | disclosed |
| EP-2794572-B1 | ACRIDINEDIONE DERIVATIVES FOR TREATING PIGMENTATION DISORDERS AND AGEING OF THE SKIN | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2016-08-03 | — | — | EP | disclosed |
| US-20140348768-A1 | ACRIDINEDIONE DERIVATIVES FOR TREATING PIGMENTATION DISORDERS AND AGEING OF THE SKIN | PIERRE FABRE DERMO COSMETIQUE (FR) | 2014-11-27 | — | — | US | disclosed |
| US-20140348768-A1 | ACRIDINEDIONE DERIVATIVES FOR TREATING PIGMENTATION DISORDERS AND AGEING OF THE SKIN | PIERRE FABRE DERMO COSMETIQUE (FR) | 2014-11-27 | — | — | US | disclosed |
| US-20140348768-A1 | ACRIDINEDIONE DERIVATIVES FOR TREATING PIGMENTATION DISORDERS AND AGEING OF THE SKIN | PIERRE FABRE DERMO COSMETIQUE (FR) | 2014-11-27 | — | — | US | disclosed |
| EP-2794572-A1 | ACRIDINEDIONE DERIVATIVES FOR TREATING PIGMENTATION DISORDERS AND AGEING OF THE SKIN | Pierre Fabre Dermo-Cosmétique (FR) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013093019-A1 | ACRIDINEDIONE DERIVATIVES FOR TREATING PIGMENTATION DISORDERS AND AGEING OF THE SKIN | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013093019-A1 | ACRIDINEDIONE DERIVATIVES FOR TREATING PIGMENTATION DISORDERS AND AGEING OF THE SKIN | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140348768-A1 | ACRIDINEDIONE DERIVATIVES FOR TREATING PIGMENTATION DISORDERS AND AGEING OF THE SKIN | TYR, PAH, AKR1C3 | KDM4E 2348/4885ALOX15 686/4885CASP1 2355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.