SCHEMBL15059232

SCHEMBL15059232

c1ccc(C(Cc2ccc3ccccc3c2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.50
CYP2A6 P11509 1/20 0.50
KMT2A Q03164 1/20 0.44
CASR P41180 2/20 0.44
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
HTR2B P41595 1/20 0.43
SIGMAR1 Q99720 1/20 0.41
MC4R P32245 1/20 0.41
MC5R P33032 1/20 0.41
SLC13A5 Q86YT5 1/20 0.41
ALOX5 P09917 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP3A4 P08684 1/20 0.40
HSD17B10 Q99714 1/20 0.40
BCHE P06276 2/20 0.40
HRH3 Q9Y5N1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19818106 0.86 CYP1A2 (0.50) CYP1A2CYP2A6CASRALOX5
SCHEMBL19818101 0.85 CYP1A2 (0.48) CYP1A2KMT2ACASRALOX5ALDH1A1
SCHEMBL19818079 0.83 CYP1A2 (0.47) CYP1A2CYP2A6CASRALOX5
SCHEMBL19818103 0.83 CYP1A2 (0.46) CYP1A2KMT2ACASRALOX5CYP3A4
SCHEMBL17023194 0.81 SLC13A5 (0.53) CYP1A2CYP2A6KMT2AHTR2AHTR2C
SCHEMBL19818102 0.79 KIF11 (0.43) CYP1A2CASRALOX5
SCHEMBL126749 0.75 CYP2C9 (0.58) CYP1A2CYP3A4
SCHEMBL19341333 0.75 CYP2A6 (0.59) CYP1A2CYP2A6KMT2ACASRHTR2A
SCHEMBL28846350 0.75 CYP1A2 (0.54) CYP1A2CYP2A6KMT2AHTR2AHTR2C
SCHEMBL28508798 0.74 SLC13A5 (0.57) CYP1A2CYP2A6HTR2ASIGMAR1SLC13A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013091660-A1 A METHOD FOR OBTAINING CRYSTALLINE LACTO-N-TETRAOSE AND LACTO-N-NEOTETRAOSE PRECURSORS AND MIXTURES THEREOF GLYCOM A/S (DK) 2013-06-27 WO disclosed