Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | SOX18 | P35713 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28508798 | 0.86 | SLC13A5 (0.57) | SLC13A5CYP1A2CYP2A6SIGMAR1SLC6A4 | |
| SCHEMBL15059232 | 0.81 | CYP1A2 (0.50) | SLC13A5CYP1A2CYP2A6SIGMAR1HRH3 | |
| SCHEMBL6240981 | 0.77 | CYP1A2 (0.65) | CYP1A2CYP2A6SIGMAR1SLC6A4HRH3 | |
| SCHEMBL29560700 | 0.77 | CYP1A2 (0.65) | CYP1A2CYP2A6SIGMAR1SLC6A4HRH3 | |
| SCHEMBL22920703 | 0.77 | CYP1A2 (0.55) | SLC13A5CYP1A2CYP2A6SIGMAR1SLC6A4 | |
| SCHEMBL8670812 | 0.76 | PLAU (0.59) | SLC13A5CYP1A2CYP2A6SIGMAR1HRH3 | |
| SCHEMBL17288660 | 0.75 | SLC13A5 (0.47) | SLC13A5CYP1A2CYP2A6SIGMAR1SLC6A4 | |
| SCHEMBL8908377 | 0.75 | MC5R (0.41) | CYP1A2CYP2A6SLC6A4KMT2AHTR2A | |
| SCHEMBL11822095 | 0.74 | CYP1A2 (0.52) | SLC13A5CYP1A2CYP2A6SIGMAR1SLC6A4 | |
| SCHEMBL17288900 | 0.74 | SIGMAR1 (0.50) | SLC13A5CYP1A2CYP2A6SIGMAR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780318-B1 | PROCESS FOR THE PRODUCTION OF N-SUBSTITUTED 2-(ACETYLAMINO)-N'-BENZYL-3-METHOXYPROPANAMIDES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2015-08-26 | — | — | EP | claimed |