Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GALR2 | O43603 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7750957 | 0.88 | ALDH1A1 (0.42) | ALDH1A1THRBPKMPOLBLMNA | |
| SCHEMBL7744963 | 0.88 | ALDH1A1 (0.42) | ALDH1A1THRBPKMPOLBLMNA | |
| SCHEMBL3353890 | 0.87 | ALDH1A1 (0.45) | ALDH1A1THRBPKMPOLBLMNA | |
| SCHEMBL7749609 | 0.86 | ALDH1A1 (0.40) | ALDH1A1THRBPKMPOLBLMNA | |
| SCHEMBL7744967 | 0.85 | POLB (0.42) | ALDH1A1THRBPOLBLMNASMN1; SMN2 | |
| SCHEMBL7752183 | 0.82 | MAPT (0.38) | ALDH1A1THRBPKMPOLBLMNA | |
| SCHEMBL5860474 | 0.82 | MEN1 (0.40) | ALDH1A1THRBPKMPOLBLMNA | |
| SCHEMBL7752175 | 0.82 | MAPT (0.38) | ALDH1A1THRBPKMPOLBLMNA | |
| SCHEMBL4715558 | 0.82 | ALDH1A1 (0.50) | ALDH1A1PKMPOLBLMNASMN1; SMN2 | |
| SCHEMBL19677066 | 0.81 | ESR1 (0.42) | ALDH1A1THRBPOLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013093928-A1 | AN IMPROVED PROCESS FOR PREPARING 2-OXINDOLES OF FORMULA I, A KEY RAW MATERIAL FOR MAKING PHARMACEUTICAL DRUGS AND INTERMEDIATES THEREOF | ARCH PHARMALABS LIMITED (IN) | 2013-06-27 | — | — | WO | disclosed |