Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GALR2 | O43603 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744967 | 0.91 | POLB (0.42) | ALDH1A1SMN1; SMN2LMNAPOLBHPGD | |
| SCHEMBL7752183 | 0.90 | MAPT (0.38) | ALDH1A1SMN1; SMN2LMNAPOLBHPGD | |
| SCHEMBL15059313 | 0.86 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2LMNAPOLBHPGD | |
| SCHEMBL7752175 | 0.85 | MAPT (0.38) | ALDH1A1SMN1; SMN2LMNAPOLBHPGD | |
| SCHEMBL18795102 | 0.84 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2LMNAPOLBHPGD | |
| SCHEMBL7750957 | 0.83 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2LMNAPOLBHPGD | |
| SCHEMBL3353890 | 0.82 | ALDH1A1 (0.45) | ALDH1A1LMNAPOLBTHRBMAPT | |
| SCHEMBL19255154 | 0.81 | MAPT (0.48) | ALDH1A1SMN1; SMN2LMNAPOLBHPGD | |
| SCHEMBL19249685 | 0.80 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2LMNAPOLBHPGD | |
| SCHEMBL492620 | 0.80 | MAPT (0.54) | ALDH1A1SMN1; SMN2LMNAHPGDMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781757-B1 | Process for the preparation of fluorinated benzoic acids | ABBOTT LAB (US) | 2001-01-03 | — | — | EP | disclosed |
| EP-0610384-B1 | PROCESS FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS | ABBOTT LAB (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0781757-A1 | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-07-02 | — | — | EP | disclosed |
| US-5637765-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-06-10 | — | — | US | disclosed |
| US-5633399-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-05-27 | — | — | US | disclosed |
| US-5576455-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1996-11-19 | — | — | US | disclosed |