Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 7/20 | 0.64 |
| ▸ | KDM2A | Q9Y2K7 | 7/20 | 0.64 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | KDM5C | P41229 | 4/20 | 0.64 |
| ▸ | KDM6B | O15054 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.42 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839290 | 0.84 | PHF8 (0.90) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| Succinylacetone SCHEMBL503918 | 0.79 | PHF8 (1.00) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL27867093 | 0.77 | EGLN1 (0.48) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL1774230 | 0.76 | EGLN1 (0.59) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL28977856 | 0.76 | EGLN1 (0.59) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL10936077 | 0.75 | KDM4E (0.55) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL26967576 | 0.75 | KDM4E (0.55) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL3221131 | 0.74 | EGLN1 (0.50) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL28887 | 0.73 | EGLN1 (0.62) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| Succinic Acid SCHEMBL8382879 | 0.73 | PHF8 (0.70) | PHF8KDM2AEGLN1KDM4EKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470874-B2 | Pharmaceutical compositions comprising cannabichromene type compounds | GW PHARMA LIMITED (GB) | 2013-06-25 | — | — | US | disclosed |
| US-8470874-B2 | Pharmaceutical compositions comprising cannabichromene type compounds | GW PHARMA LIMITED (GB) | 2013-06-25 | — | — | US | disclosed |