Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.37 |
| ▸ | ACHE | P22303 | 6/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | KDM5A | P29375 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 9/20 | 0.33 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23703653 | 0.93 | BCHE (0.44) | BCHEACHEKDM4CEPHX2KDM5A | |
| SCHEMBL499666 | 0.88 | KMT2A (0.33) | PHF8KDM2A | |
| SCHEMBL22205611 | 0.81 | LMNA (0.44) | KDM4CKDM5AALDH1A1KDM4AKDM7A | |
| SCHEMBL24703880 | 0.81 | ALDH1A1 (0.42) | KDM4CKDM5AALDH1A1KDM4AKDM7A | |
| SCHEMBL3292418 | 0.79 | ALDH1A1 (0.54) | BCHEACHEKDM4CEPHX2KDM5A | |
| SCHEMBL29991123 | 0.79 | ALDH1A1 (0.41) | BCHEACHEKDM4CKDM5AALDH1A1 | |
| SCHEMBL6577360 | 0.79 | MEN1 (0.33) | KDM4CKDM5A | |
| SCHEMBL27153792 | 0.78 | TSHR (0.50) | KDM4CKDM5AALDH1A1KDM4AKDM7A | |
| SCHEMBL380215 | 0.78 | HDAC6 (0.43) | BCHEACHECHRM2CHRM1 | |
| SCHEMBL380216 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230142285-A1 | SUBSTITUTED STRAIGHT CHAIN SPIRO DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2023-05-11 | — | — | US | disclosed |
| US-8476253-B2 | Amide derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142285-A1 | SUBSTITUTED STRAIGHT CHAIN SPIRO DERIVATIVES | MLLT1, MEN1, MLLT3 | BCHE 4880/4885ACHE 4885/4885KDM4C 2512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.