SCHEMBL15061823

SCHEMBL15061823

CC(C)(C)[Si](OCC1OC(n2cc(I)c3c(N)ncnc32)CC1N=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ ADK P55263 11/20 0.42
▸ HASPIN Q8TF76 1/20 0.38
▸ CA2 P00918 1/20 0.37
▸ PRMT5 O14744 3/20 0.37
▸ METTL3 Q86U44 3/20 0.37
▸ MTOR P42345 1/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ SRC P12931 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2611647 0.88 ADK (0.47) ADKCA2PRMT5METTL3MTOR
SCHEMBL20810837 0.88 ADK (0.47) ADKCA2PRMT5METTL3MTOR
SCHEMBL20810884 0.75 ADK (0.38) ADKCA2PRMT5METTL3
SCHEMBL2611648 0.75 ADK (0.38) ADKCA2PRMT5METTL3
SCHEMBL2611628 0.74 CA2 (0.48) ADKCA2PRMT5METTL3
SCHEMBL18214121 0.74 CA2 (0.47) ADKCA2PRMT5METTL3
SCHEMBL29720474 0.74 ADK (0.52) ADKCA2PRMT5METTL3MTOR
SCHEMBL22815042 0.74 ADK (0.30) ADK
SCHEMBL17111225 0.74 ADK (0.47) ADKHASPINPRMT5METTL3MTOR
SCHEMBL17106786 0.74 ADK (0.47) ADKHASPINPRMT5METTL3MTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2607369-A1 Modified nucleotides for polynucleotide sequencing Illumina Cambridge Limited (GB) 2013-06-26 — — EP disclosed
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