Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23498902 | 0.85 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HPGDMAPTCA12 | |
| SCHEMBL27259271 | 0.84 | APLNR (0.44) | ALDH1A1SMN1; SMN2HPGDMAPTCA12 | |
| SCHEMBL155605 | 0.79 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2HPGDMAPTCA12 | |
| SCHEMBL154900 | 0.79 | HTT (0.49) | ALDH1A1SMN1; SMN2HPGDMAPTGAA | |
| SCHEMBL158429 | 0.79 | HPGD (0.38) | ALDH1A1SMN1; SMN2HPGDMAPTCA12 | |
| SCHEMBL27259664 | 0.78 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HPGDMAPTCA12 | |
| SCHEMBL19438592 | 0.77 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2HPGDMAPTCA12 | |
| SCHEMBL3139605 | 0.76 | HPGD (0.36) | ALDH1A1SMN1; SMN2HPGDMAPTCA12 | |
| SCHEMBL1316433 | 0.76 | NOTUM (0.57) | ALDH1A1SMN1; SMN2HPGDMAPTCA12 | |
| SCHEMBL23498987 | 0.76 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2HPGDMAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973910-B1 | PYRROLO[3,2-C]PYRIDINE-4-ONE 2-INDOLINONE PROTEIN KINASE INHIBITORS | SHANGHAI HENGRUI PHARM CO LTD (CN) | 2013-06-26 | — | — | EP | disclosed |