Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.77 |
| ▸ | HTR2A | P28223 | 4/20 | 0.77 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.77 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.77 |
| ▸ | HTR2B | P41595 | 2/20 | 0.77 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.77 |
| ▸ | HTR1A | P08908 | 1/20 | 0.77 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.77 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | HRH1 | P35367 | 1/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
| ▸ | HTR3A | P46098 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 2/20 | 0.50 |
| ▸ | HTR1B | P28222 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3175037 | 0.89 | SLC6A4 (0.70) | SLC6A4HTR2ASLC6A2SLC6A3HTR2B | |
| Viloxazine SCHEMBL29359040 | 0.87 | SLC6A4 (1.00) | SLC6A4HTR2ASLC6A2SLC6A3HTR2B | |
| SCHEMBL6161190 | 0.87 | ADRA2C (1.00) | SLC6A4HTR2ASLC6A2SLC6A3HTR2B | |
| (R)-Viloxazine SCHEMBL30589854 | 0.87 | SLC6A4 (1.00) | SLC6A4HTR2ASLC6A2SLC6A3HTR2B | |
| (R)-Viloxazine SCHEMBL2524727 | 0.87 | SLC6A4 (1.00) | SLC6A4HTR2ASLC6A2SLC6A3HTR2B | |
| (S)-Viloxazine SCHEMBL31126415 | 0.87 | SLC6A4 (1.00) | SLC6A4HTR2ASLC6A2SLC6A3HTR2B | |
| Viloxazine SCHEMBL34168 | 0.87 | SLC6A4 (1.00) | SLC6A4HTR2ASLC6A2SLC6A3HTR2B | |
| (S)-Viloxazine SCHEMBL2524730 | 0.87 | SLC6A4 (1.00) | SLC6A4HTR2ASLC6A2SLC6A3HTR2B | |
| (S)-Viloxazine SCHEMBL25394508 | 0.86 | SLC6A4 (0.97) | SLC6A4HTR2ASLC6A2SLC6A3HTR2B | |
| Viloxazine SCHEMBL300741 | 0.86 | SLC6A4 (0.97) | SLC6A4HTR2ASLC6A2SLC6A3HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607364-A1 | Tetraaza-cyclopenta[a]indenyl and their use as positive allosteric modulators | Ares Trading S.A. (CH) | 2013-06-26 | — | — | EP | disclosed |