Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 9/20 | 0.34 |
| ▸ | SLC6A15 | Q9H2J7 | 5/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15062309 | 0.66 | PTGS1 (0.33) | ALOX15MEN1NPC1MAPTRAB9A | |
| SCHEMBL15062289 | 0.60 | FABP4 (0.35) | MEN1NPC1TP53RAB9AKMT2A | |
| SCHEMBL11807931 | 0.58 | SRD5A1 (0.56) | HRH1SLC6A15ALOX15MEN1NPC1 | |
| SCHEMBL3596705 | 0.57 | MAPT (0.47) | MEN1LMNAMAPTCYP2C9MAPK1 | |
| SCHEMBL18070225 | 0.56 | UGCG (0.47) | MEN1NPC1LMNAMAPTMAPK1 | |
| SCHEMBL15594517 | 0.56 | KDM4E (0.45) | MEN1LMNACYP2D6MAPTRAB9A | |
| SCHEMBL2064320 | 0.56 | MEN1 (0.53) | HRH1SLC6A15ALOX15MEN1NPC1 | |
| SCHEMBL12213204 | 0.55 | MEN1 (0.44) | HRH1SLC6A15ALOX15MEN1NPC1 | |
| SCHEMBL31293460 | 0.55 | OPRM1 (0.42) | MEN1CYP2D6CYP2C19OPRM1KMT2A | |
| SCHEMBL5709337 | 0.55 | MEN1 (0.44) | HRH1SLC6A15ALOX15MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2179994-B1 | FUSED BICYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2013-06-26 | — | — | EP | disclosed |