SCHEMBL15062350

SCHEMBL15062350

CCCCOCC(CCC(C)C)(COCCCC)C(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19514177 0.89 HSD17B10 (0.34)
SCHEMBL8466662 0.89 LMNA (0.39)
SCHEMBL8464212 0.80
SCHEMBL8465972 0.77 CES1 (0.43) TSHRCES1
SCHEMBL28661174 0.75 CYP3A4 (0.49) TSHR
SCHEMBL2496381 0.74
SCHEMBL13517839 0.72 OPRM1 (0.30)
SCHEMBL7939046 0.71
SCHEMBL234416 0.71
SCHEMBL13517851 0.71 OPRM1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170066852-A1 CATALYST COMPONENT BOREALIS AG (AT) 2017-03-09 US claimed
EP-2610273-B1 Catalyst component BOREALIS AG (AT) 2018-02-07 EP disclosed
US-20170066852-A1 CATALYST COMPONENT BOREALIS AG (AT) 2017-03-09 US disclosed
US-20140378298-A1 CATALYST COMPONENT BOREALIS AG (AT) 2014-12-25 US disclosed
WO-2013098139-A1 CATALYST COMPONENT BOREALIS AG (AT) 2013-07-04 WO disclosed
EP-2610273-A1 Catalyst component Borealis AG (AT) 2013-07-03 EP disclosed