Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11195885 | 0.91 | CASP6 (0.75) | CASP6LMNATSHRHCAR3 | |
| SCHEMBL11781006 | 0.87 | TDP1 (0.61) | CASP6LMNATDP1MEN1KMT2A | |
| SCHEMBL20591997 | 0.87 | TP53 (0.51) | CASP6LMNATDP1MEN1KMT2A | |
| SCHEMBL5958796 | 0.84 | TDP1 (0.65) | LMNATDP1MEN1KMT2ATSHR | |
| SCHEMBL17197945 | 0.83 | CASP6 (0.68) | CASP6LMNATSHRHCAR3 | |
| Hydrochloric Acid SCHEMBL9784149 | 0.82 | CASP6 (0.62) | CASP6LMNATDP1TSHRTTR | |
| SCHEMBL9557826 | 0.81 | CASP6 (0.66) | CASP6LMNATDP1TSHRHCAR3 | |
| SCHEMBL23499234 | 0.80 | CASP6 (0.64) | CASP6LMNATDP1TSHRHCAR3 | |
| SCHEMBL31548567 | 0.80 | CASP6 (0.64) | CASP6LMNAMEN1KMT2ATSHR | |
| SCHEMBL30011381 | 0.80 | CASP6 (0.64) | CASP6LMNATDP1TSHRHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797946-B1 | SIALIC ACID DIMERS | BROSSMER REINHARD (DE) | 2016-05-04 | — | — | EP | disclosed |
| US-9260467-B2 | Sialic acid dimers | BROSSMER REINHARD (DE) | 2016-02-16 | — | — | US | disclosed |
| US-20150005245-A1 | Sialic Acid Dimers | BROSSMER REINHARD (DE) | 2015-01-01 | — | — | US | disclosed |
| EP-2797946-A1 | SIALIC ACID DIMERS | Brossmer, Reinhard (DE) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013097942-A1 | SIALIC ACID DIMERS | BROSSMER REINHARD (DE) | 2013-07-04 | — | — | WO | disclosed |
| EP-2610263-A1 | Sialic acid dimers | Brossmer, Reinhard (DE) | 2013-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005245-A1 | Sialic Acid Dimers | SIGLEC9, SIGLEC7, NEU2 | CASP6 1945/4885LMNA 924/4885TDP1 4267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.