Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 5/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL516223 | 0.78 | TDP1 (0.36) | IL1BPIM1PIM2SRD5A1KAT2B | |
| SCHEMBL4071388 | 0.78 | TDP1 (0.36) | IL1BPIM1PIM2SRD5A1KAT2B | |
| SCHEMBL195122 | 0.78 | TDP1 (0.36) | IL1BPIM1PIM2SRD5A1KAT2B | |
| SCHEMBL7708607 | 0.70 | IL1B (0.35) | IL1BPIM1PIM2SRD5A1KAT2B | |
| SCHEMBL558118 | 0.70 | IL1B (0.35) | IL1BPIM1PIM2SRD5A1KAT2B | |
| SCHEMBL516879 | 0.70 | IL1B (0.35) | IL1BPIM1PIM2SRD5A1 | |
| SCHEMBL590224 | 0.70 | IL1B (0.35) | IL1BPIM1PIM2SRD5A1 | |
| SCHEMBL31491349 | 0.70 | IL1B (0.35) | IL1BPIM1PIM2SRD5A1 | |
| SCHEMBL10266156 | 0.68 | IL1B (0.38) | IL1BPIM1PIM2 | |
| SCHEMBL15491222 | 0.61 | SRD5A1 (0.44) | IL1BSRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2610258-A1 | Substituted piperidino dihydrothieno pyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-03 | — | — | EP | disclosed |