Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15062792 | 0.94 | L3MBTL1 (0.51) | MEN1KMT2ATSHRL3MBTL1MAPT | |
| SCHEMBL3082495 | 0.85 | KMT2A (0.50) | MEN1KMT2AL3MBTL1MAPTAKR1C3 | |
| SCHEMBL3084581 | 0.83 | CPT1A (0.51) | MEN1KMT2ATSHRL3MBTL1MAPT | |
| SCHEMBL3088413 | 0.82 | MEN1 (0.49) | MEN1KMT2ATSHRL3MBTL1MAPT | |
| SCHEMBL15062809 | 0.82 | AKR1C3 (0.58) | MEN1KMT2AL3MBTL1PDE4BPDE4D | |
| SCHEMBL3082454 | 0.81 | MEN1 (0.50) | MEN1KMT2ATSHRL3MBTL1MAPT | |
| SCHEMBL3089841 | 0.80 | KMT2A (0.55) | MEN1KMT2ATSHRL3MBTL1MAPT | |
| SCHEMBL13261231 | 0.80 | MEN1 (0.51) | MEN1KMT2ATSHRL3MBTL1MAPT | |
| SCHEMBL15062737 | 0.79 | AKR1C3 (0.46) | L3MBTL1AKR1C3SMN1; SMN2 | |
| SCHEMBL13180947 | 0.79 | MEN1 (0.50) | MEN1KMT2ATSHRL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393812-B1 | SUBSTITUTED SPIROAMIDES AS B1R-MODULATORS | GRUENENTHAL GMBH (DE) | 2013-07-03 | — | — | EP | disclosed |