Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 19/20 | 0.59 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180572 | 0.87 | MEN1 (0.57) | DGAT1SOAT1 | |
| SCHEMBL183567 | 0.86 | DGAT1 (0.57) | DGAT1SOAT1 | |
| SCHEMBL180791 | 0.84 | CYP1A1 (0.54) | DGAT1 | |
| SCHEMBL181062 | 0.83 | DGAT1 (0.70) | DGAT1SOAT1 | |
| SCHEMBL14617028 | 0.83 | DGAT1 (0.70) | DGAT1SOAT1 | |
| SCHEMBL13664073 | 0.83 | DGAT1 (0.70) | DGAT1SOAT1 | |
| SCHEMBL13664059 | 0.82 | DGAT1 (0.64) | DGAT1SOAT2SOAT1 | |
| SCHEMBL180787 | 0.82 | DGAT1 (0.64) | DGAT1SOAT2SOAT1 | |
| SCHEMBL16546762 | 0.82 | DGAT1 (0.64) | DGAT1SOAT2SOAT1 | |
| SCHEMBL181036 | 0.78 | DGAT1 (0.61) | DGAT1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402317-B1 | DGAT inhibitor | NOVARTIS AG (CH) | 2013-07-03 | — | — | EP | disclosed |