Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 13/20 | 0.57 |
| ▸ | CDC7 | O00311 | 1/20 | 0.53 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.51 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.51 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.49 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15062884 | 0.86 | DGAT1 (0.59) | DGAT1SOAT1 | |
| SCHEMBL180787 | 0.85 | DGAT1 (0.64) | DGAT1SOAT1 | |
| SCHEMBL13664059 | 0.85 | DGAT1 (0.64) | DGAT1SOAT1 | |
| SCHEMBL16546762 | 0.85 | DGAT1 (0.64) | DGAT1SOAT1 | |
| SCHEMBL181062 | 0.83 | DGAT1 (0.70) | DGAT1SOAT1 | |
| SCHEMBL13664073 | 0.83 | DGAT1 (0.70) | DGAT1SOAT1 | |
| SCHEMBL14617028 | 0.83 | DGAT1 (0.70) | DGAT1SOAT1 | |
| SCHEMBL180791 | 0.81 | CYP1A1 (0.54) | DGAT1 | |
| SCHEMBL180572 | 0.81 | MEN1 (0.57) | DGAT1SOAT1 | |
| SCHEMBL181036 | 0.78 | DGAT1 (0.61) | DGAT1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402318-A1 | DGAT inhibitors | Novartis AG (CH) | 2012-01-04 | — | — | EP | disclosed |