SCHEMBL150633

SCHEMBL150633

[c]1ccc2c3cc[c]c4cccc(c5cccc1c25)c43

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.35
ALDH1A1 P00352 1/20 0.35
THRB P10828 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CYP2A6 P11509 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1046556 1.00 CYP1A2 (0.35) CYP1A2ALDH1A1THRBHPGDHSD17B10
SCHEMBL989382 0.91 ALDH1A1 (0.44) CYP1A2ALDH1A1THRBHPGDHSD17B10
SCHEMBL16396033 0.87
SCHEMBL2408476 0.82 CYP1A2 (0.38) CYP1A2ALDH1A1THRBHPGDHSD17B10
SCHEMBL2413155 0.82 CYP1A2 (0.38) CYP1A2ALDH1A1THRBHPGDHSD17B10
SCHEMBL1081612 0.81 ALDH1A1 (0.32) CYP1A2ALDH1A1THRBHPGDHSD17B10
SCHEMBL2411403 0.81 ALDH1A1 (0.32) CYP1A2ALDH1A1THRBHPGDHSD17B10
SCHEMBL1899901 0.77 ALDH1A1 (0.61) CYP1A2ALDH1A1THRBHPGDHSD17B10
SCHEMBL2407910 0.75 CYP1A2 (0.39) CYP1A2ALDH1A1THRBHPGDHSD17B10
SCHEMBL2407073 0.74 CYP1A2 (0.38) CYP1A2ALDH1A1THRBHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 509 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110382491-B Crosslinkable organometallic luminescent ligands and complexes 洛马克斯有限公司 2023-10-20 CN claimed
WO-2023164642-A2 CHIRAL BAND EDGE EMISSION ENHANCED ORGANIC LIGHT EMITTING DIODE-BASED DEVICES THAT EMIT MULTIPLE LIGHT WAVELENGTHS RED BANK TECHNOLOGIES LLC (US) 2023-08-31 WO claimed
EP-3592737-B1 CROSS-LINKABLE ORGANOMETALLIC LIGHT EMITTING COMPLEXES LOMOX LTD (GB) 2022-12-21 EP claimed
US-11316118-B2 Dibenzo[d,B]silole-based reactive mesogens LOMOX LIMITED (GB) 2022-04-26 US claimed
EP-3523313-B1 DIBENZO[D,B]SILOLE-BASED REACTIVE MESOGENS LOMOX LTD (GB) 2021-05-05 EP claimed
US-20190280223-A1 DIBENZO[D,B]SILOLE-BASED REACTIVE MESOGENS LOMOX LIMITED (GB) 2019-09-12 US claimed
EP-3523313-A1 DIBENZO[D,B]SILOLE-BASED REACTIVE MESOGENS Lomox Limited (GB) 2019-08-14 EP claimed
US-10131678-B2 Method for producing branched oligoarylsilanes LUMINESCENT INNOVATION TECHNOLOGIES LLC (RU) 2018-11-20 US claimed
WO-2018162880-A1 CROSS-LINKABLE ORGANOMETALLIC LIGHT EMITTING LIGANDS AND COMPLEXES LOMOX LIMITED (GB) 2018-09-13 WO claimed
EP-3006486-B1 NOVEL BRANCHED OLIGOARYLSILANES AND METHOD FOR PRODUCING SAME LUMINESCENT INNOVATION TECH LIMITED LIABILITY COMPANY (RU) 2018-08-08 EP claimed
US-20090005505-A1 polymeric light emitting diodes; longer operating lifetime; brightness with lower energy; MERCK PATENT GMBH (DE) 2009-01-01 US claimed
EP-1741149-B1 ELECTROLUMINESCENT POLYMERS AND USE THEROF MERCK PATENT GMBH (DE) 2008-12-24 EP claimed
EP-1961016-A1 TRIARYLAMINE-ARYLVINYLENE MOIETY-CONTAINING CONJUGATED POLYMERS, THEIR PRODUCTION AND USE Merck Patent GmbH (DE) 2008-08-27 EP claimed
WO-2008019744-A1 CONJUGATED POLYMERS, PROCESS FOR THEIR PREPARATION AND THEIR USE MERCK PATENT GMBH (DE) 2008-02-21 WO claimed
WO-2008011967-A1 1,4-BIS(2-THIENYLVINYL)BENZOL DERIVATIVES AND THEIR USE MERCK PATENT GMBH (DE) 2008-01-31 WO claimed
US-20070205714-A1 Electroluminescent Polymers and the Use Thereof MERCK PATENT GMBH (DE) 2007-09-06 US claimed
WO-2007068325-A1 TRIARYLAMINE-ARYLVINYLENE MOIETY-CONTAINING CONJUGATED POLYMERS, THEIR PRODUCTION AND USE MERCK PATENT GMBH (DE) 2007-06-21 WO claimed
US-20070123690-A1 Conjugated polymers, representation thereof, and use of the same MERCK PATENT GMBH (DE) 2007-05-31 US claimed
EP-1709699-A1 CONJUGATED POLYMERS, REPRESENTATION THEREOF, AND USE OF THE SAME MERCK PATENT GmbH (DE) 2006-10-11 EP claimed
WO-2005053054-A1 CONJUGATED POLYMERS, REPRESENTATION THEREOF, AND USE OF THE SAME MERCK PATENT GMBH (DE) 2005-06-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190280223-A1 DIBENZO[D,B]SILOLE-BASED REACTIVE MESOGENS CCNB1, CCNE2, UBE2G2 CYP1A2 151/4885ALDH1A1 107/4885THRB 1640/4885
US-11316118-B2 Dibenzo[d,B]silole-based reactive mesogens CCNB1, CCNE2, UBE2G2 CYP1A2 151/4885ALDH1A1 107/4885THRB 1640/4885
US-10131678-B2 Method for producing branched oligoarylsilanes SIK2, SIK3, SIK1 CYP1A2 3435/4885ALDH1A1 4313/4885THRB 824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.