SCHEMBL2408476

SCHEMBL2408476

[c]1ccc2c3[c]ccc4cccc(c5cccc1c25)c43

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38
THRB P10828 1/20 0.38
ERBB2 P04626 1/20 0.32
FYN P06241 1/20 0.32
MAOA P21397 1/20 0.32
ACHE P22303 1/20 0.32
AHR P35869 1/20 0.32
CYP1A1 P04798 1/20 0.30
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
CYP1B1 Q16678 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2413155 1.00 CYP1A2 (0.38) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL2407910 0.87 CYP1A2 (0.39) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL1047443 0.87 ALDH1A1 (0.44) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL989382 0.87 ALDH1A1 (0.44) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL2410185 0.87 ALDH1A1 (0.42) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL15936077 0.86 CYP1A2 (0.39) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL2405885 0.82 ALDH1A1 (0.48) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL1046556 0.82 CYP1A2 (0.35) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL150633 0.82 CYP1A2 (0.35) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL2410430 0.81 ALDH1A1 (0.41) CYP1A2ALDH1A1HPGDHSD17B10THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011105700-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2011-09-01 WO disclosed