Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL593692 | 0.94 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1TSHRTDP1 | |
| Lithium Ion SCHEMBL28357757 | 0.78 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1TSHRTDP1 | |
| Lithium Ion SCHEMBL5013311 | 0.74 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1 | |
| Lithium Ion SCHEMBL5013308 | 0.74 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1 | |
| SCHEMBL30400834 | 0.73 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1TSHRTDP1 | |
| SCHEMBL14673901 | 0.72 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1TSHR | |
| SCHEMBL26694521 | 0.72 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1TSHRTDP1 | |
| SCHEMBL26694768 | 0.72 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1TSHRTDP1 | |
| Silver SCHEMBL2351578 | 0.72 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1TSHRTDP1 | |
| SCHEMBL593037 | 0.71 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8956799-B2 | Photoacid generator and photoresist comprising same | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2015-02-17 | — | — | US | disclosed |
| US-20130171567-A1 | PHOTOACID GENERATOR AND PHOTORESIST COMPRISING SAME | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2013-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130171567-A1 | PHOTOACID GENERATOR AND PHOTORESIST COMPRISING SAME | F10, C1S, H1-0 | ALDH1A1 472/4885L3MBTL1 2736/4885TSHR 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.