SCHEMBL15063643

SCHEMBL15063643

[c]1cccc(-c2cc(-c3ccccc3)cc(-c3cccc(-c4cc(-c5ccccc5)cc(-c5ccccc5)c4)c3)c2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.41
KMO O15229 1/20 0.41
ALDH1A1 P00352 1/20 0.39
MEN1 O00255 1/20 0.38
ESR1 P03372 1/20 0.38
KMT2A Q03164 1/20 0.38
DHODH Q02127 1/20 0.38
ABL1 P00519 2/20 0.38
ABCB1 P08183 2/20 0.38
BCR P11274 2/20 0.38
MGLL Q99685 2/20 0.38
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
ACMSD Q8TDX5 1/20 0.36
GP6 Q9HCN6 1/20 0.36
ALOX5 P09917 1/20 0.35
PRSS1 P07477 1/20 0.35
PRSS2 P07478 1/20 0.35
PRSS3 P35030 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24793 0.98 MAOA (0.43) MAOAKMOALDH1A1MEN1ESR1
SCHEMBL2449354 0.98 MAOA (0.43) MAOAKMOALDH1A1MEN1ESR1
SCHEMBL2449105 0.96 ALDH1A1 (0.43) MAOAKMOALDH1A1DHODHALOX5
SCHEMBL17200836 0.91 MEN1 (0.39) MAOAKMOMEN1ESR1KMT2A
SCHEMBL17200853 0.91 MEN1 (0.39) MAOAKMOMEN1ESR1KMT2A
SCHEMBL11972750 0.89 ALDH1A1 (0.41) MAOAKMOALDH1A1MEN1ESR1
SCHEMBL2960 0.89 ALDH1A1 (0.50) MAOAALDH1A1MGLLALOX5CYP1A2
SCHEMBL11973149 0.87 MEN1 (0.38) MAOAKMOMEN1ESR1KMT2A
SCHEMBL2448213 0.86 ALDH1A1 (0.47) ALDH1A1MGLLALOX5CYP1A1CYP1A2
SCHEMBL24983 0.86 ALDH1A1 (0.47) ALDH1A1MGLLALOX5CYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9287514-B2 Metal complex and device using the metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-03-15 US disclosed
US-20130168615-A1 METAL COMPLEX AND DEVICE USING THE METAL COMPLEX NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2013-07-04 US disclosed