Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL72939 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL153476 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL28576576 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1401747 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL22476039 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL150902 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3237788 | 0.94 | — | — | |
| Bicarbonate SCHEMBL14563499 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL40504 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL14563712 | 0.89 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220219142-A1 | POLYMERIC LANTHANUM NANOCOMPOSITE, AND PREPARATION METHOD AND APPLICATION THEREOF | NANJING UNIVERSITY (CN) | 2022-07-14 | — | — | US | claimed |
| US-8962036-B2 | Disintegrable formulations of lanthanum carbonate | MYLAN PHARMACEUTICALS INC. (US) | 2015-02-24 | — | — | US | claimed |
| EP-2429950-B1 | PROCESS FOR THE PREPARATION OF LANTHANUM CARBONATE DIHYDRATE | NATCO PHARMA LTD (IN) | 2013-04-17 | — | — | EP | claimed |
| EP-2429950-A1 | PROCESS FOR THE PREPARATION OF LANTHANUM CARBONATE DIHYDRATE | Natco Pharma Limited (IN) | 2012-03-21 | — | — | EP | claimed |
| US-20120058200-A1 | PROCESS FOR THE PREPARATION OF LANTHANUM CARBONATE DIHYDRATE | NATCO PHARMA LIMITED (IN) | 2012-03-08 | — | — | US | claimed |
| EP-2389070-A1 | DISINTEGRABLE FORMULATIONS OF LANTHANUM CARBONATE | Mylan Inc. (US) | 2011-11-30 | — | — | EP | claimed |
| US-20110280967-A1 | DISINTEGRABLE FORMULATIONS OF LANTHANUM CARBONATE | MYLAN INC. (US) | 2011-11-17 | — | — | US | claimed |
| US-20110253641-A1 | Filter Sleeve for Enabling Waste Water Discharge Directly into the Environment | PEARSE HERB R | 2011-10-20 | — | — | US | claimed |
| WO-2010131255-A1 | PROCESS FOR THE PREPARATION OF LANTHANUM CARBONATE DIHYDRATE | NATCO PHARMA LIMITED (IN) | 2010-11-18 | — | — | WO | claimed |
| WO-2010085520-A1 | DISINTEGRABLE FORMULATIONS OF LANTHANUM CARBONATE | MYLAN INC. (US) | 2010-07-29 | — | — | WO | claimed |
| US-7192609-B2 | Use of rare earth compounds for the prevention of kidney stone disease | SHIRE INTERNATIONAL LICENSING B.V. (NL) | 2007-03-20 | — | — | US | claimed |
| WO-2023108907-A1 | FUSED IRON CATALYST FOR PREPARING HIGH-CARBON α OLEFIN FROM SYNTHESIS GAS, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海兖矿能源科技研发有限公司 | 2023-06-22 | — | — | WO | disclosed |
| US-20220219142-A1 | POLYMERIC LANTHANUM NANOCOMPOSITE, AND PREPARATION METHOD AND APPLICATION THEREOF | NANJING UNIVERSITY (CN) | 2022-07-14 | — | — | US | disclosed |
| CN-113559797-B | Biochar aerogel material and preparation method and application thereof | 云南大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-114130406-A | Molten iron catalyst for preparing high-carbon alpha olefin from synthesis gas and preparation method and application thereof | 上海兖矿能源科技研发有限公司 | 2022-03-04 | — | — | CN | disclosed |
| EP-1529015-A2 | RARE EARTH METAL COMPOUNDS, METHODS OF MAKING, AND METHODS OF USING THE SAME | Altair Nanomaterials Inc. (US) | 2005-05-11 | — | — | EP | disclosed |
| US-20040161474-A1 | Rare earth metal compounds methods of making, and methods of using the same | SPECTRUM PHARMACEUTICALS, INC. | 2004-08-19 | — | — | US | disclosed |
| WO-2004016553-A2 | RARE EARTH METAL COMPOUNDS, METHODS OF MAKING, AND METHODS OF USING THE SAME | ALTAIR NANOMATERIALS INC. (US) | 2004-02-26 | — | — | WO | disclosed |
| US-5272132-A | Apparatus comprising a ceramic superconductive body and method for producing such a body | AT&T BELL LABORATORIES (US) | 1993-12-21 | — | — | US | disclosed |
| EP-0283197-A2 | Apparatus comprising a superconductive body, and method for producing such a body | AT&T Corp. (US) | 1988-09-21 | — | — | EP | disclosed |