Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15081865 | 0.82 | CHRM2 (0.45) | HTTNPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL6591574 | 0.78 | STS (0.52) | HTTNPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL12104302 | 0.76 | HSD11B1 (0.39) | HTTNPC1RAB9ASMN1; SMN2CHRM2 | |
| SCHEMBL19798473 | 0.74 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2CHRNA7HTR3A | |
| SCHEMBL21814874 | 0.74 | APP (0.45) | HTTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL22791795 | 0.72 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL19798477 | 0.70 | CHRNA7 (0.51) | HTTNPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL28525201 | 0.69 | SMN1; SMN2 (0.55) | HTTNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL23758327 | 0.69 | MAPT (0.46) | NPC1RAB9ASMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL22127250 | 0.69 | KDM1A (0.47) | HTTNPC1RAB9ASMN1; SMN2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023092175-A1 | NOVEL P2X7 RECEPTOR ANTAGONISTS | THE UNIVERSITY OF SYDNEY (AU) | 2023-06-01 | — | — | WO | disclosed |
| US-20130172570-A1 | METHOD OF MAKING BENZAZOLES | US GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2013-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172570-A1 | METHOD OF MAKING BENZAZOLES | NBAS, CBR3, CBR1 | HTT 1164/4885NPC1 163/4885RAB9A 2393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.