⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL820783 | 0.75 | CA2 (0.35) | — | |
| SCHEMBL437818 | 0.75 | — | — | |
| SCHEMBL28101062 | 0.73 | — | — | |
| SCHEMBL28417042 | 0.73 | FDPS (0.37) | — | |
| SCHEMBL29168431 | 0.71 | — | — | |
| SCHEMBL31178353 | 0.67 | TSHR (0.30) | — | |
| SCHEMBL31393230 | 0.67 | PPARD (0.34) | — | |
| SCHEMBL27937178 | 0.67 | ANPEP (0.31) | — | |
| SCHEMBL31367023 | 0.65 | KDM4E (0.43) | — | |
| SCHEMBL31464011 | 0.65 | FDPS (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8519110-B2 | mRNA cap analogs | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2013-08-27 | — | — | US | disclosed |
| EP-2297175-B1 | MRNA CAP ANALOGS | UNIV WARSZAWSKI (PL) | 2013-08-07 | — | — | EP | disclosed |
| US-20110092574-A1 | mRNA Cap Analogs | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-04-21 | — | — | US | disclosed |
| EP-2297175-A2 | MRNA CAP ANALOGS | Uniwersytet Warszawski (PL) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009149253-A2 | MRNA CAP ANALOGS | UNIWERSYTET WARSZAWSKI (PL) | 2009-12-10 | — | — | WO | disclosed |