SCHEMBL15065201

SCHEMBL15065201

[c]1cc2ccccc2c2c1OC=CC2

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30536504 0.70 KDM4E (0.45) KDM4EMAPT
SCHEMBL8021672 0.70 KDM4E (0.45) KDM4EMAPT
SCHEMBL3247520 0.67 CDK2 (0.35) KDM4EMAPT
SCHEMBL30476323 0.67 TDP1 (0.42) KDM4EMAPT
SCHEMBL29719907 0.64 GPR84 (0.46) KDM4EMAPT
SCHEMBL9986878 0.63 HSD17B10 (0.37) KDM4EMAPT
SCHEMBL15065200 0.63 CYP1A1 (0.33)
SCHEMBL3226155 0.61 BCHE (0.35) KDM4E
SCHEMBL16766410 0.61 BCHE (0.35) KDM4EMAPT
SCHEMBL2412691 0.60 ALDH1A1 (0.43) KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4003968-A1 PROCESS FOR PREPARING A COUMARIN-CAGED FORSKOLIN DERIVATIVE, FORSKOLIN DERIVATIVE AND USE OF SAID FORSKOLIN DERIVATIVE Forschungszentrum Jülich GmbH (DE) 2022-06-01 EP claimed
WO-2021013278-A1 PROCESS FOR PREPARING A COUMARIN-CAGED FORSKOLIN DERIVATIVE, FORSKOLIN DERIVATIVE AND USE OF SAID FORSKOLIN DERIVATIVE Forschungszentrum Jülich GmbH (DE) 2021-01-28 WO claimed
US-20130174289-A1 Na+/Mg2+ Exchanger FBN - LEIBNITZ-INSTITUT FUR NUTZTIERBIOLOGIE (DE) 2013-07-04 US disclosed