Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18455272 | 0.74 | CYP1A2 (0.34) | CYP1A2 | |
| SCHEMBL1397027 | 0.73 | CYP1A2 (0.45) | CYP1A2POLBALOX15ALDH1A1TSHR | |
| SCHEMBL28041791 | 0.73 | — | — | |
| SCHEMBL15065760 | 0.72 | CYP1A2 (0.35) | CYP1A2 | |
| SCHEMBL29556678 | 0.72 | CYP1A2 (0.35) | CYP1A2 | |
| SCHEMBL11690149 | 0.69 | NPSR1 (0.31) | ALOX15ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL645408 | 0.68 | ALDH1A1 (0.33) | ALOX15ALDH1A1TSHR | |
| SCHEMBL3887504 | 0.67 | — | — | |
| SCHEMBL5465101 | 0.67 | — | — | |
| SCHEMBL24900445 | 0.66 | CYP1A2 (0.53) | CYP1A2ALOX15ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797897-B1 | 2,6-DIHALO-5-ALKOXY-4-SUBSTITUTED-PYRIMIDINES, PYRIMIDINE- CARBALDEHYDES, AND METHODS OF FORMATION AND USE | DOW AGROSCIENCES LLC (US) | 2017-02-01 | — | — | EP | disclosed |
| EP-2797897-B1 | 2,6-DIHALO-5-ALKOXY-4-SUBSTITUTED-PYRIMIDINES, PYRIMIDINE- CARBALDEHYDES, AND METHODS OF FORMATION AND USE | DOW AGROSCIENCES LLC (US) | 2017-02-01 | — | — | EP | disclosed |
| US-9216958-B2 | 2,6-dihalo-5-alkoxy-4-substituted-pyrimidines, pyrimidine-carbaldehydes, and methods of formation and use | DOW AGROSCIENCES LLC (US) | 2015-12-22 | — | — | US | disclosed |
| US-9216958-B2 | 2,6-dihalo-5-alkoxy-4-substituted-pyrimidines, pyrimidine-carbaldehydes, and methods of formation and use | DOW AGROSCIENCES LLC (US) | 2015-12-22 | — | — | US | disclosed |
| US-9216958-B2 | 2,6-dihalo-5-alkoxy-4-substituted-pyrimidines, pyrimidine-carbaldehydes, and methods of formation and use | DOW AGROSCIENCES LLC (US) | 2015-12-22 | — | — | US | disclosed |
| US-20150031883-A1 | 2,6-DIHALO-5-ALKOXY-4-SUBSTITUTED-PYRIMIDINES, PYRIMIDINE-CARBALDEHYDES, AND METHODS OF FORMATION AND USE | CORTEVA AGRISCIENCE LLC | 2015-01-29 | — | — | US | disclosed |
| US-20150031883-A1 | 2,6-DIHALO-5-ALKOXY-4-SUBSTITUTED-PYRIMIDINES, PYRIMIDINE-CARBALDEHYDES, AND METHODS OF FORMATION AND USE | CORTEVA AGRISCIENCE LLC | 2015-01-29 | — | — | US | disclosed |
| US-20150031883-A1 | 2,6-DIHALO-5-ALKOXY-4-SUBSTITUTED-PYRIMIDINES, PYRIMIDINE-CARBALDEHYDES, AND METHODS OF FORMATION AND USE | CORTEVA AGRISCIENCE LLC | 2015-01-29 | — | — | US | disclosed |
| EP-2797897-A1 | 2,6-DIHALO-5-ALKOXY-4-SUBSTITUTED-PYRIMIDINES, PYRIMIDINE- CARBALDEHYDES, AND METHODS OF FORMATION AND USE | Dow AgroSciences LLC (US) | 2014-11-05 | — | — | EP | disclosed |
| US-8877925-B2 | 2,6-dihalo-5-alkoxy-4-substituted-pyrimidines, pyrimidine-carbaldehydes, and methods of formation and use | DOW AGROSCIENCES, LLC. (US) | 2014-11-04 | — | — | US | disclosed |
| US-8877925-B2 | 2,6-dihalo-5-alkoxy-4-substituted-pyrimidines, pyrimidine-carbaldehydes, and methods of formation and use | DOW AGROSCIENCES, LLC. (US) | 2014-11-04 | — | — | US | disclosed |
| US-8877925-B2 | 2,6-dihalo-5-alkoxy-4-substituted-pyrimidines, pyrimidine-carbaldehydes, and methods of formation and use | DOW AGROSCIENCES, LLC. (US) | 2014-11-04 | — | — | US | disclosed |
| US-20130172557-A1 | 2,6-DIHALO-5-ALKOXY-4-SUBSTITUTED-PYRIMIDINES, PYRIMIDINE- CARBALDEHYDES, AND METHODS OF FORMATION AND USE | DOW AGROSCIENCES LLC (US) | 2013-07-04 | — | — | US | disclosed |
| US-20130172557-A1 | 2,6-DIHALO-5-ALKOXY-4-SUBSTITUTED-PYRIMIDINES, PYRIMIDINE- CARBALDEHYDES, AND METHODS OF FORMATION AND USE | DOW AGROSCIENCES LLC (US) | 2013-07-04 | — | — | US | disclosed |
| US-20130172557-A1 | 2,6-DIHALO-5-ALKOXY-4-SUBSTITUTED-PYRIMIDINES, PYRIMIDINE- CARBALDEHYDES, AND METHODS OF FORMATION AND USE | DOW AGROSCIENCES LLC (US) | 2013-07-04 | — | — | US | disclosed |
| WO-2013102111-A1 | 2,6-DIHALO-5-ALKOXY-4-SUBSTITUTED-PYRIMIDINES, PYRIMIDINE- CARBALDEHYDES, AND METHODS OF FORMATION AND USE | DOW AGROSCIENCES LLC (US) | 2013-07-04 | — | — | WO | disclosed |
| WO-2013102111-A1 | 2,6-DIHALO-5-ALKOXY-4-SUBSTITUTED-PYRIMIDINES, PYRIMIDINE- CARBALDEHYDES, AND METHODS OF FORMATION AND USE | DOW AGROSCIENCES LLC (US) | 2013-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172557-A1 | 2,6-DIHALO-5-ALKOXY-4-SUBSTITUTED-PYRIMIDINES, PYRIMIDINE- CARBALDEHYDES, AND METHODS OF FORMATION AND USE | DPYD, DDT, DCTD | CYP1A2 388/4885DHFR 10/4885CYP3A4 428/4885 |
| US-20150031883-A1 | 2,6-DIHALO-5-ALKOXY-4-SUBSTITUTED-PYRIMIDINES, PYRIMIDINE-CARBALDEHYDES, AND METHODS OF FORMATION AND USE | DPYD, DDT, DCTD | CYP1A2 388/4885DHFR 10/4885CYP3A4 428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.