Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15065924 | 0.91 | SLC6A2 (0.52) | SLC6A2SLC6A3SLC6A4KDM4EALDH1A1 | |
| SCHEMBL15066031 | 0.90 | SLC6A3 (0.52) | SLC6A2SLC6A3SLC6A4KDM4EPOLB | |
| SCHEMBL15065487 | 0.86 | SLC6A2 (0.48) | SLC6A2SLC6A3SLC6A4KDM4EALDH1A1 | |
| SCHEMBL15066246 | 0.85 | SLC6A3 (0.56) | SLC6A2SLC6A3SLC6A4KDM4EPOLB | |
| SCHEMBL15065551 | 0.82 | SLC6A3 (0.67) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL15065883 | 0.81 | SLC6A2 (0.52) | SLC6A2SLC6A3SLC6A4KDM4EALDH1A1 | |
| SCHEMBL15066381 | 0.80 | SLC6A3 (0.55) | SLC6A2SLC6A3SLC6A4KDM4EHPGD | |
| SCHEMBL15065898 | 0.79 | SLC6A3 (0.53) | SLC6A2SLC6A3SLC6A4CHRM2CHRM1 | |
| SCHEMBL15066416 | 0.79 | SLC6A3 (0.53) | SLC6A2SLC6A3SLC6A4KDM4EALDH1A1 | |
| SCHEMBL15066503 | 0.78 | SLC6A2 (0.53) | SLC6A2SLC6A3SLC6A4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797870-A1 | COMPOSITIONS, SYNTHESIS, AND METHODS OF USING PHENYLCYCLOALKYLMETHYLAMINE DERIVATIVES | Reviva Pharmaceuticals, Inc. (US) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013102195-A1 | COMPOSITIONS, SYNTHESIS, AND METHODS OF USING PHENYLCYCLOALKYLMETHYLAMINE DERIVATIVES | REVIVA PHARMACEUTICALS, INC. (US) | 2013-07-04 | — | — | WO | disclosed |