Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15066503 | 0.97 | SLC6A2 (0.53) | SLC6A2SLC6A3SLC6A4CASP1GAA | |
| SCHEMBL15066388 | 0.93 | SLC6A2 (0.50) | SLC6A2SLC6A3SLC6A4CASP1GAA | |
| SCHEMBL15066357 | 0.91 | SLC6A2 (0.53) | SLC6A2SLC6A3SLC6A4CASP1GAA | |
| SCHEMBL15066405 | 0.88 | SLC6A2 (0.54) | SLC6A2SLC6A3SLC6A4CASP1GAA | |
| SCHEMBL15065902 | 0.85 | SLC6A2 (0.51) | SLC6A2SLC6A3SLC6A4CASP1GAA | |
| SCHEMBL15065551 | 0.85 | SLC6A3 (0.67) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL15066518 | 0.83 | SLC6A2 (0.50) | SLC6A2SLC6A3SLC6A4CASP1GAA | |
| SCHEMBL15065659 | 0.82 | SLC6A2 (0.49) | SLC6A2SLC6A3SLC6A4CASP1GAA | |
| SCHEMBL15066246 | 0.82 | SLC6A3 (0.56) | SLC6A2SLC6A3SLC6A4KDM4E | |
| SCHEMBL15065372 | 0.81 | SLC6A2 (0.53) | SLC6A2SLC6A3SLC6A4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797870-A1 | COMPOSITIONS, SYNTHESIS, AND METHODS OF USING PHENYLCYCLOALKYLMETHYLAMINE DERIVATIVES | Reviva Pharmaceuticals, Inc. (US) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013102195-A1 | COMPOSITIONS, SYNTHESIS, AND METHODS OF USING PHENYLCYCLOALKYLMETHYLAMINE DERIVATIVES | REVIVA PHARMACEUTICALS, INC. (US) | 2013-07-04 | — | — | WO | disclosed |