Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12769099 | 0.90 | ALDH1A1 (0.48) | ESR2ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2044506 | 0.89 | ALDH1A1 (0.54) | ESR2ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL27471526 | 0.89 | ALDH1A1 (0.54) | ESR2ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2044509 | 0.89 | ALDH1A1 (0.54) | ESR2ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3161832 | 0.84 | PDE4A (0.52) | ESR2ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1515026 | 0.83 | DRD2 (0.59) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPK1 | |
| SCHEMBL14403055 | 0.83 | ESR2 (0.78) | ESR2KMT2APDE4APDE4BPDE4C | |
| SCHEMBL31019748 | 0.81 | HRH3 (0.53) | ESR2ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4601394 | 0.80 | TSHR (0.56) | ESR2ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4602856 | 0.80 | HRH3 (0.56) | ESR2SMN1; SMN2MAPK1CRBNHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119409615-A | 2- (Indol-3-yl) phenol compound and synthesis method thereof | 湘潭大学 | 2025-02-11 | — | — | CN | claimed |
| CN-113296310-A | Quantum dot light conversion layer and preparation method thereof | 广东普加福光电科技有限公司 | 2021-08-24 | — | — | CN | claimed |
| CN-107619386-B | Aromatic ring [ c ] carbazole derivative and synthesis method thereof | 湘潭大学 | 2020-10-13 | — | — | CN | claimed |
| CN-107619386-A | A kind of aromatic ring simultaneously [c] carbazole analog derivative and its synthetic method | 湘潭大学 | 2018-01-23 | — | — | CN | claimed |
| US-20250281515-A1 | CARBORANE COMPOUNDS, CARBORANE ANALOGS, AND METHODS OF USE THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2025-09-11 | — | — | US | disclosed |
| US-20250270210-A1 | BCL-2 Inhibitor | BEIGENE, LTD. (KY) | 2025-08-28 | — | — | US | disclosed |
| US-12286430-B2 | Bcl-2 inhibitor | BEIGENE, LTD. (KY) | 2025-04-29 | — | — | US | disclosed |
| CN-119409615-A | 2- (Indol-3-yl) phenol compound and synthesis method thereof | 湘潭大学 | 2025-02-11 | — | — | CN | disclosed |
| US-20240376097-A1 | BCL-2 Inhibitor | BEIGENE LTD. (KY) | 2024-11-14 | — | — | US | disclosed |
| EP-4460492-A1 | COMPOUNDS CONTAINING A HYDROXYPHENYL MOIETY AND THEIR USE | (INSERM) Institut National de la Santé et de la Recherche Médicale (FR) | 2024-11-13 | — | — | EP | disclosed |
| CN-113347979-B | Carborane compounds, carborane analogs, and methods of use thereof | 俄亥俄州创新基金会 | 2024-08-16 | — | — | CN | disclosed |
| CN-116969936-A | BCL-2 inhibitors | 百济神州有限公司 | 2023-10-31 | — | — | CN | disclosed |
| US-20010056179-A1 | Selective linear peptides with melanocortin-4 receptor (MC4-R) agonist activity | HOFFMANN-LA ROCHE INC. | 2001-12-27 | — | — | US | disclosed |
| WO-2001074844-A2 | SELECTIVE LINEAR PEPTIDES WITH MELANOCORTIN-4 RECEPTOR (MC4-R) AGONIST ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2001-10-11 | — | — | WO | disclosed |
| WO-2001060846-A1 | CYCLIC HEXAPEPTIDE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-23 | — | — | WO | disclosed |
| EP-0893424-A1 | ALPHA,ALPHA-DIFLUOROBENZYL ETHER DERIVATIVES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORPORATION (JP) | 1999-01-27 | — | — | EP | disclosed |
| WO-1998031697-A1 | ARYL C-GLYCOSIDE COMPOUNDS AND SULFATED ESTERS THEREOF | SANKYO COMPANY, LIMITED (JP) | 1998-07-23 | — | — | WO | disclosed |
| US-5712281-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |
| EP-0303398-B1 | PREPARATION PROCESS OF 4-(4-HYDROXYPHENYL)-CYCLOHEXANOL | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4894487-A | Preparation process of 4-(4-hydroxyphenyl)-cyclohexanol | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1990-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270210-A1 | BCL-2 Inhibitor | BCL2, BCL2A1, BCL2L1 | ESR2 1033/4885ALDH1A1 2918/4885SMN1; SMN2 1721/4885 |
| US-20240376097-A1 | BCL-2 Inhibitor | BCL2, BCL2A1, BCL2L1 | ESR2 1033/4885ALDH1A1 2918/4885SMN1; SMN2 1721/4885 |
| US-12286430-B2 | Bcl-2 inhibitor | BCL2, BCL2A1, BCL2L1 | ESR2 1033/4885ALDH1A1 2918/4885SMN1; SMN2 1721/4885 |
| US-20250281515-A1 | CARBORANE COMPOUNDS, CARBORANE ANALOGS, AND METHODS OF USE THEREOF | ESR2, ESRRB, ESRRA | ESR2 1/4885ALDH1A1 1094/4885SMN1; SMN2 788/4885 |
| US-20010056179-A1 | Selective linear peptides with melanocortin-4 receptor (MC4-R) agonist activity | MC4R, MC3R, MC1R | ESR2 1169/4885ALDH1A1 4684/4885SMN1; SMN2 2762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.