Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134397 | 0.97 | PIM1 (0.39) | PIM1PAOXKDM4EALDH1A1LMNA | |
| SCHEMBL14142584 | 0.97 | PIM1 (0.39) | PIM1PAOXKDM4EALDH1A1LMNA | |
| SCHEMBL19212956 | 0.97 | PIM1 (0.39) | PIM1PAOXKDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL8203320 | 0.95 | PIM1 (0.38) | PIM1PAOXKDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7648633 | 0.93 | PIM1 (0.37) | PIM1PAOXKDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7648636 | 0.93 | PIM1 (0.37) | PIM1PAOXKDM4EALDH1A1LMNA | |
| SCHEMBL3418369 | 0.91 | PIM1 (0.36) | PIM1PAOXKDM4EALDH1A1LMNA | |
| SCHEMBL1186740 | 0.89 | — | — | |
| SCHEMBL2231151 | 0.89 | PIM1 (0.42) | PIM1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL2920396 | 0.89 | CHKA (0.43) | SIGMAR1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9644066-B2 | Cyclic amine compounds, compositions, and polyurethane foams made therefrom | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-05-09 | — | — | US | claimed |
| EP-2797902-B1 | COMPOSITIONS CONTAINING CYCLIC AMINE COMPOUNDS, AND POLYURETHANE FOAMS MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-04-26 | — | — | EP | claimed |
| US-20150005404-A1 | CYCLIC AMINE COMPOUNDS, COMPOSITIONS, AND POLYURETHANE FOAMS MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC | 2015-01-01 | — | — | US | claimed |
| EP-2797902-A2 | CYCLIC AMINE COMPOUNDS, COMPOSITIONS, AND POLYURETHANE FOAMS MADE THEREFROM | Dow Global Technologies LLC (US) | 2014-11-05 | — | — | EP | claimed |
| WO-2013102097-A2 | CYCLIC AMINE COMPOUNDS, COMPOSITIONS, AND POLYURETHANE FOAMS MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-07-04 | — | — | WO | claimed |
| US-9644066-B2 | Cyclic amine compounds, compositions, and polyurethane foams made therefrom | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-05-09 | — | — | US | disclosed |
| EP-2797902-B1 | COMPOSITIONS CONTAINING CYCLIC AMINE COMPOUNDS, AND POLYURETHANE FOAMS MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-04-26 | — | — | EP | disclosed |
| US-20150005404-A1 | CYCLIC AMINE COMPOUNDS, COMPOSITIONS, AND POLYURETHANE FOAMS MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC | 2015-01-01 | — | — | US | disclosed |
| EP-2797902-A2 | CYCLIC AMINE COMPOUNDS, COMPOSITIONS, AND POLYURETHANE FOAMS MADE THEREFROM | Dow Global Technologies LLC (US) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013102097-A2 | CYCLIC AMINE COMPOUNDS, COMPOSITIONS, AND POLYURETHANE FOAMS MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005404-A1 | CYCLIC AMINE COMPOUNDS, COMPOSITIONS, AND POLYURETHANE FOAMS MADE THEREFROM | PUF60, UFM1, POLM | PIM1 3314/4885PAOX 886/4885KDM4E 1785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.