⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231151 | 1.00 | PIM1 (0.42) | — | |
| SCHEMBL14142584 | 0.92 | PIM1 (0.39) | — | |
| SCHEMBL134397 | 0.92 | PIM1 (0.39) | — | |
| SCHEMBL19212956 | 0.92 | PIM1 (0.39) | — | |
| SCHEMBL31085356 | 0.89 | DRD2 (0.41) | — | |
| SCHEMBL15065746 | 0.89 | PIM1 (0.38) | — | |
| SCHEMBL5986738 | 0.89 | PIM1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL8203320 | 0.89 | PIM1 (0.38) | — | |
| SCHEMBL9927905 | 0.88 | — | — | |
| SCHEMBL3671614 | 0.88 | SIGMAR1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778584-A1 | PRODUCTION PROCESS OF 2-CHLORO-4-HETEROARYL-PYRIMIDINE DERIVATIVES | ARIAD Pharmaceuticals, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |
| EP-3409669-B1 | HETEROARYL COMPOUNDS FOR KINASE INHIBITION | ARIAD PHARMA INC (US) | 2020-10-07 | — | — | EP | disclosed |
| EP-3607915-A1 | ADHESION PROMOTING PRIMER FOR COATED SURFACES | Cardinal Health Switzerland 515 GmbH (CH) | 2020-02-12 | — | — | EP | disclosed |
| EP-2198814-B1 | Adhesion promoting primer for coated surfaces | CARDINAL HEALTH 515 GMBH (CH) | 2019-06-05 | — | — | EP | disclosed |
| US-9796712-B2 | Heteroaryl compounds for kinase inhibition | ARIAD PHARMACEUTICALS, INC. (US) | 2017-10-24 | — | — | US | disclosed |
| US-20170253594-A1 | HETEROARYL COMPOUNDS FOR KINASE INHIBITION | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-09-07 | — | — | US | disclosed |
| US-20170197962-A1 | HETEROARYL COMPOUNDS FOR KINASE INHIBITION | ARIAD PHARMACEUTICALS, INC. | 2017-07-13 | — | — | US | disclosed |
| US-20170166598-A1 | HETEROARYL COMPOUNDS FOR KINASE INHIBITION | ARIAD PHARMACEUTICALS, INC. | 2017-06-15 | — | — | US | disclosed |
| WO-2015195228-A1 | HETEROARYL COMPOUNDS FOR KINASE INHIBITION | ARIAD PHARMACEUTICALS, INC. (US) | 2015-12-23 | — | — | WO | disclosed |
| EP-2201915-B1 | Adhesion promoting temporary mask for coated surfaces | CORDIS CORP (US) | 2015-05-27 | — | — | EP | disclosed |
| US-8927049-B2 | Adhesion promoting temporary mask for coated surfaces | CORDIS CORPORATION | 2015-01-06 | — | — | US | disclosed |
| US-20110029070-A1 | ADHESION PROMOTING PRIMER FOR COATED SURFACES | CORDIS US CORP | 2011-02-03 | — | — | US | disclosed |
| US-20100304007-A1 | ADHESION PROMOTING TEMPORARY MASK FOR COATED SURFACES | ACCESS CLOSURE, INC. | 2010-12-02 | — | — | US | disclosed |
| US-7819914-B2 | Adhesion promoting primer for coated surfaces | CORDIS CORPORATION (US) | 2010-10-26 | — | — | US | disclosed |
| EP-2213264-A1 | Reservoir eluting stent | Cordis Corporation (US) | 2010-08-04 | — | — | EP | disclosed |
| EP-2201915-A1 | Adhesion promoting temporary mask for coated surfaces | Cordis Corporation (US) | 2010-06-30 | — | — | EP | disclosed |
| US-20100161039-A1 | ADHESION PROMOTING TEMPORARY MASK FOR COATED SURFACES | CORDIS US CORP | 2010-06-24 | — | — | US | disclosed |
| EP-2198814-A2 | Adhesion promoting primer for coated surfaces | Cordis Corporation (US) | 2010-06-23 | — | — | EP | disclosed |
| US-20100152841-A1 | ADHESION PROMOTING PRIMER FOR COATED SURFACES | CORDIS US CORP | 2010-06-17 | — | — | US | disclosed |