SCHEMBL3418369

SCHEMBL3418369

C1CN2CCN1CC2.CN(C)CCN1CCN(C)CC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.36
SIGMAR1 Q99720 7/20 0.35
PAOX Q6QHF9 1/20 0.34
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
PTK2B Q14289 1/20 0.34
ESR2 Q92731 1/20 0.34
USP2 O75604 1/20 0.33
HPGD P15428 1/20 0.33
MC4R P32245 1/20 0.32
ACKR3 P25106 1/20 0.32
CA12 O43570 1/20 0.32
CA2 P00918 1/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL134397 0.93 PIM1 (0.39) PIM1SIGMAR1PAOXALDH1A1KDM4E
SCHEMBL14142584 0.93 PIM1 (0.39) PIM1SIGMAR1PAOXALDH1A1KDM4E
SCHEMBL19212956 0.93 PIM1 (0.39) PIM1SIGMAR1PAOXALDH1A1KDM4E
Hydrochloric Acid SCHEMBL8203320 0.91 PIM1 (0.38) PIM1SIGMAR1PAOXALDH1A1KDM4E
SCHEMBL15065746 0.91 PIM1 (0.38) PIM1SIGMAR1PAOXALDH1A1KDM4E
Hydrochloric Acid SCHEMBL7648633 0.88 PIM1 (0.37) PIM1SIGMAR1PAOXALDH1A1KDM4E
Hydrochloric Acid SCHEMBL7648636 0.88 PIM1 (0.37) PIM1SIGMAR1PAOXALDH1A1KDM4E
SCHEMBL2231151 0.85 PIM1 (0.42) PIM1SIGMAR1ALDH1A1KDM4ELMNA
SCHEMBL1186740 0.85
SCHEMBL2920396 0.84 CHKA (0.43) SIGMAR1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2396123-B1 COMPOSITIONS FOR MULTILAYER COATING AND RESINS THEREFORE SHERWIN WILLIAMS CO (US) 2015-06-03 EP disclosed
US-8334347-B2 Compositions for multilayer coating and resins therefore THE SHERWIN-WILLIAMS COMPANY (US) 2012-12-18 US disclosed
US-20120308830-A1 COATING SYSTEM COMPRISING HIGH ACID RESIN THE SHERWIN-WILLIAMS COMPANY (US) 2012-12-06 US disclosed
US-20100203251-A1 COMPOSITIONS FOR MULTILAYER COATING AND RESINS THEREFORE THE SHERWIN-WILLIAMS COMPANY (US) 2010-08-12 US disclosed
US-7459167-B1 Biocidal polyurethane compositions and methods of use 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-12-02 US disclosed
EP-0022497-B1 PROCESS FOR THE PREPARATION OF ELASTIC, OPTIONALLY CELLULAR POLYURETHANE UREAS BAYER AG (DE) 1983-05-11 EP disclosed
US-4013701-A PROCESS FOR THE PRODUCTION OF POLYISOCYANATES BAYER AKTIENGESELLSCHAFT (DT) 1977-03-22 US disclosed