Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 3/20 | 0.39 |
| ▸ | CCKAR | P32238 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12781048 | 0.85 | SCN9A (0.42) | CCKBRCCKARSCN9ASRC | |
| SCHEMBL6517624 | 0.81 | KCNH2 (0.45) | CCKBRCCKARSCN9A | |
| SCHEMBL12781055 | 0.80 | CCKBR (0.43) | CCKBRCCKARSCN9A | |
| SCHEMBL16498272 | 0.78 | KCNH2 (0.43) | CCKBRCCKARSCN9A | |
| SCHEMBL7543309 | 0.78 | CCKBR (0.47) | CCKBRSCN9ABDKRB1 | |
| SCHEMBL7543311 | 0.78 | CCKBR (0.47) | CCKBRSCN9ABDKRB1 | |
| SCHEMBL16498120 | 0.78 | CCKBR (0.42) | CCKBRCCKARSCN9A | |
| SCHEMBL7417336 | 0.72 | NPY1R (0.51) | CCKBRSCN9A | |
| SCHEMBL8610939 | 0.71 | SENP1 (0.70) | CCKBRSCN9A | |
| SCHEMBL6516243 | 0.70 | CCKBR (0.49) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011027156-A1 | BENZODIAZEPINE DERIVATIVES FOR TREATING HEPATITIS C INFECTION | ARROW THERAPEUTICS LIMITED (GB) | 2011-03-10 | — | — | WO | disclosed |
| US-20110059043-A1 | CHEMICAL COMPOUNDS | ARROW THERAPEUTICS LIMITED (GB) | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059043-A1 | CHEMICAL COMPOUNDS | CYP2E1, CNR1, CYP3A5 | CCKBR 180/4885CCKAR 183/4885SCN9A 2227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.