Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248588 | 0.80 | HDAC8 (0.46) | HDAC8EPHX1GAACYP3A4CYP1A2 | |
| SCHEMBL19254238 | 0.78 | HDAC8 (0.46) | HDAC8EPHX1GAACYP3A4CYP1A2 | |
| SCHEMBL15066568 | 0.74 | HDAC8 (0.45) | HDAC8CYP3A4CYP1A2CYP2D6ALOX15 | |
| SCHEMBL23347536 | 0.71 | ATM (0.48) | HDAC8EPHX1GAAMETAP2METAP1 | |
| SCHEMBL15088574 | 0.71 | EPHX1 (0.42) | HDAC8EPHX1GAACYP3A4CYP2C9 | |
| SCHEMBL4983591 | 0.70 | HDAC8 (0.51) | HDAC8EPHX1GAACYP2D6CYP2C19 | |
| SCHEMBL9780834 | 0.68 | CYP3A4 (0.52) | HDAC8EPHX1GAACYP3A4CYP1A2 | |
| SCHEMBL6005671 | 0.68 | CYP3A4 (0.52) | HDAC8EPHX1GAACYP3A4CYP1A2 | |
| SCHEMBL30035044 | 0.68 | ALDH1A1 (0.50) | GAACYP3A4CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL697972 | 0.68 | ALDH1A1 (0.63) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797881-A1 | Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same | Bio-Pharm Solutions Co., Ltd. (KR) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013100566-A1 | Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2013-07-04 | — | — | WO | disclosed |