Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15068402 | 0.81 | MTNR1A (0.39) | L3MBTL1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL18600542 | 0.79 | AKR1B1 (0.39) | TDP1KMT2AALDH1A1KDM4E | |
| SCHEMBL28366194 | 0.71 | TSHR (0.51) | TDP1L3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL15160348 | 0.71 | ALDH1A1 (0.35) | KMT2AALDH1A1 | |
| SCHEMBL28362405 | 0.71 | TSHR (0.54) | TDP1L3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL28137294 | 0.71 | ALDH1A1 (0.52) | TDP1L3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL28366032 | 0.70 | TSHR (0.53) | TDP1L3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL28580608 | 0.69 | NPSR1 (0.60) | CNR2TDP1L3MBTL1TSHRMEN1 | |
| SCHEMBL2422452 | 0.69 | TDP1 (0.47) | TDP1L3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL20766473 | 0.69 | CCR8 (0.45) | KMT2AALDH1A1KDM4ELMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797416-A1 | SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | Global Blood Therapeutics, Inc. (US) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013102142-A1 | SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2013-07-04 | — | — | WO | disclosed |