⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4864412 | 0.78 | — | — | |
| SCHEMBL7246168 | 0.78 | — | — | |
| SCHEMBL6240800 | 0.78 | — | — | |
| SCHEMBL6466885 | 0.78 | — | — | |
| SCHEMBL29258492 | 0.77 | KDM1A (0.43) | — | |
| SCHEMBL4140258 | 0.75 | CCR1 (0.41) | — | |
| SCHEMBL1515429 | 0.75 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL1092283 | 0.75 | P4HTM (0.33) | — | |
| SCHEMBL642783 | 0.73 | — | — | |
| SCHEMBL2643095 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115626893-B | Synthesis method of 2-hydroxy-5-hydroxymethylpyridine | 山西永津集团有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-115626893-A | Synthesis method of 2-hydroxy-5-hydroxymethylpyridine | 山西永津集团有限公司 | 2023-01-20 | — | — | CN | claimed |
| US-6022974-A | Process for the production of 2-chloro-5-chloromethyl-pyridine | LONZA LTD. (CH) | 2000-02-08 | — | — | US | claimed |
| EP-0569947-B1 | Process for the production of 2-chloro-5-chloromethyl-pyridine | LONZA AG (CH) | 1995-03-01 | — | — | EP | claimed |
| EP-0569947-A1 | Process for the production of 2-chloro-5-chloromethyl-pyridine | LONZA AG (CH) | 1993-11-18 | — | — | EP | claimed |
| JP-6032779-A | — | — | None | — | — | JP | disclosed |
| JP-6237780-A | — | — | None | — | — | JP | disclosed |
| JP-7224037-A | — | — | None | — | — | JP | disclosed |
| CN-115626893-B | Synthesis method of 2-hydroxy-5-hydroxymethylpyridine | 山西永津集团有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115626893-B | Synthesis method of 2-hydroxy-5-hydroxymethylpyridine | 山西永津集团有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115626893-B | Synthesis method of 2-hydroxy-5-hydroxymethylpyridine | 山西永津集团有限公司 | 2024-04-02 | — | — | CN | disclosed |
| EP-3689868-B1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | ARVINAS OPERATIONS INC (US) | 2023-09-27 | — | — | EP | disclosed |
| US-6022974-A | Process for the production of 2-chloro-5-chloromethyl-pyridine | LONZA LTD. (CH) | 2000-02-08 | — | — | US | disclosed |
| US-6022974-A | Process for the production of 2-chloro-5-chloromethyl-pyridine | LONZA LTD. (CH) | 2000-02-08 | — | — | US | disclosed |
| JP-H07224037-A | PRODUCTION OF 3-HYDROXYMETHYL-6-HYDROXYPYRIDINE | MITSUBISHI CHEM CORP | 1995-08-22 | — | — | JP | disclosed |
| EP-0569947-B1 | Process for the production of 2-chloro-5-chloromethyl-pyridine | LONZA AG (CH) | 1995-03-01 | — | — | EP | disclosed |
| JP-H06237780-A | PRODUCTION OF PYRIDINE DERIVATIVE | MITSUBISHI KASEI CORP | 1994-08-30 | — | — | JP | disclosed |
| JP-H0632779-A | PREPARATION OF 2-CHLORO-5-CHLOROMETHYL-PYRIDINE | LONZA AG | 1994-02-08 | — | — | JP | disclosed |
| EP-0569947-A1 | Process for the production of 2-chloro-5-chloromethyl-pyridine | LONZA AG (CH) | 1993-11-18 | — | — | EP | disclosed |
| EP-0569947-A1 | Process for the production of 2-chloro-5-chloromethyl-pyridine | LONZA AG (CH) | 1993-11-18 | — | — | EP | disclosed |